Exploration of metal-ligand coordination bonds in proteins by single-molecule force spectroscopy
J Nie, F Tian, B Zheng, Z Wang, P Zheng - Chemistry Letters, 2021 - academic.oup.com
Thanks to the binding of various metal ions, metalloprotein plays an essential role in many
different biological processes and represents an indispensable protein subgroup. Thus, the …
different biological processes and represents an indispensable protein subgroup. Thus, the …
Boosting the electrochemical detection response toward hydroxychloroquine via tungsten trioxide nanorods/nitrogen-doped carbon nanofiber nanocomposite
The overusage of hydroxychloroquine (HQ) amidst the outbreak of coronavirus disease has
contributed to increased fatalities concerning HQ poisoning. Hence, there is an utmost …
contributed to increased fatalities concerning HQ poisoning. Hence, there is an utmost …
[PDF][PDF] A review on the mechanism of action of favipiravir and hydroxychloroquine in COVID-19
V Pavlova, S Hristova, K Uzunova, T Vekov - Res. Rev. Insights, 2021 - researchgate.net
The global COVID-19 pandemic, caused by the severe acute respiratory syndrome-
coronavirus 2 (SARS-CoV-2), spread rapidly across the globe. The lack of available …
coronavirus 2 (SARS-CoV-2), spread rapidly across the globe. The lack of available …
New insights into the mechanism of action of the drug chloroquine: direct interaction with DNA and cytotoxicity
EA Costa, AP Gonçalves, JAD Batista… - The Journal of …, 2022 - ACS Publications
Chloroquine (CLQ) and hydroxychloroquine (HCLQ) are compounds largely employed in
the treatment of various human diseases for decades. Nevertheless, a number of intrinsic …
the treatment of various human diseases for decades. Nevertheless, a number of intrinsic …
Groove switching of hydroxychloroquine modulates the efficacy of binding and induced stability to DNA
Hydroxychloroquine (HCQ) is an important drug for the treatment of rheumatoid arthritis and
malaria. HCQ targets specifically to nucleic acids for its action. However, the mechanism of …
malaria. HCQ targets specifically to nucleic acids for its action. However, the mechanism of …
Caffeine modulates the intercalation of drugs on DNA: A study at the single molecule level
We use optical tweezers to characterize the ability of Caffeine (Caf) to modulate the
intercalation of drugs into the DNA double-helix at the single molecule level. When …
intercalation of drugs into the DNA double-helix at the single molecule level. When …
Studying the structure, BSA and FS-DNA interaction, fluorescence sensing of anions, cytotoxicity, and catecholase activity of Cu (II) and Zn (II) Schiff base complexes
Synthesis, characterization, X-ray crystallography, and the interaction with BSA/FS-DNA are
reported for two new complexes,[{Cu II 2 L (NCS) 2}(μ 1, 3-NCS)] n (1) and [Zn II 2 L (μ 1, 1 …
reported for two new complexes,[{Cu II 2 L (NCS) 2}(μ 1, 3-NCS)] n (1) and [Zn II 2 L (μ 1, 1 …
Contrasting Effect of Salts on the Binding of Antimalarial Drug Hydroxychloroquine with Different Sequences of Duplex DNA
Hydroxychloroquine (HCQ) is an important antimalarial drug which functions plausibly by
targeting the DNA of parasites. Salts play a crucial role in the functionality of various …
targeting the DNA of parasites. Salts play a crucial role in the functionality of various …
抑菌剂与DNA 作用方式的研究方法.
王德娴， 胡新月， 宋丽雅 - Journal of Food Safety & Quality, 2022 - search.ebscohost.com
防腐剂是食品工业中不可缺少的物质, 但是食品防腐剂仍存在种类少, 耐药性和安全性等问题,
新型抑菌剂的研发及其作用机制研究已经成为研究者们关注的重点. 脱氧核糖核苷酸(DNA) …
新型抑菌剂的研发及其作用机制研究已经成为研究者们关注的重点. 脱氧核糖核苷酸(DNA) …
On the interactions involving serine proteases obtained from Monacrosporium thaumasium (Ascomycota: Orbiliomycetes) and deoxyribonucleic acid (DNA) …
LSC Altoé, E de Araújo Costa, GP Tavares… - Archives of …, 2023 - Springer
The use of force spectroscopy approaches performed with optical tweezers can be very
useful in determining the binding modes and the physical chemistry of DNA interactions with …
useful in determining the binding modes and the physical chemistry of DNA interactions with …