Effect of fluoride on cytotoxicity involved in mitochondrial dysfunction: a review of mechanism
M Wei, Y Ye, MM Ali, Y Chamba, J Tang… - Frontiers in veterinary …, 2022 - frontiersin.org
Fluoride is commonly found in the soil and water environment and may act as chronic
poison. A large amount of fluoride deposition causes serious harm to the ecological …
poison. A large amount of fluoride deposition causes serious harm to the ecological …
Recent advances in cellular effects of fluoride: an update on its signalling pathway and targeted therapeutic approaches
Fluoride is a natural element essential in minute quantities in human's to maintain dental
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …
and skeletal health. However, the disease fluorosis manifests itself due to excessive fluoride …
[HTML][HTML] Fluoride exposure during pregnancy and lactation triggers oxidative stress and molecular changes in hippocampus of offspring rats
Long-term exposure to high concentrations of fluoride (F) can damage mineralized and soft
tissues such as bones, liver, kidney, intestine, and nervous system of adult rats. The high …
tissues such as bones, liver, kidney, intestine, and nervous system of adult rats. The high …
Fluoride induced neurobehavioral impairments in experimental animals: a brief review
Fluoride is one of the major toxicants in the environment and is often found in drinking water
at higher concentrations. Living organisms including humans exposed to high fluoride levels …
at higher concentrations. Living organisms including humans exposed to high fluoride levels …
Effects of fluoride exposure on mitochondrial function: energy metabolism, dynamics, biogenesis and mitophagy
SH Avila-Rojas, OE Aparicio-Trejo… - Environmental …, 2022 - Elsevier
Fluoride is ubiquitous in the environment. Furthermore, drinking water represents the main
source of exposure to fluoride for humans. Interestingly, low fluoride concentrations have …
source of exposure to fluoride for humans. Interestingly, low fluoride concentrations have …
[HTML][HTML] F-53B mediated ROS affects uterine development in rats during puberty by inducing apoptosis
P Nie, Y Lan, T You, T Jia, H Xu - Ecotoxicology and Environmental Safety, 2024 - Elsevier
Perfluoroalkyl and polyfluoroalkyl substances (PFASs), as pollutants, can cause palpable
environmental and health impacts around the world, as endocrine disruptors, can disrupt …
environmental and health impacts around the world, as endocrine disruptors, can disrupt …
Effects of fluoride long-term exposure over the cerebellum: global proteomic profile, oxidative biochemistry, cell density, and motor behavior evaluation
GO Lopes, MK Martins Ferreira, L Davis… - International journal of …, 2020 - mdpi.com
Although the literature does not provide evidence of health risks from exposure to fluoride
(F) in therapeutic doses, questions remain about the effects of long-term and high-dose use …
(F) in therapeutic doses, questions remain about the effects of long-term and high-dose use …
[HTML][HTML] Nrf2/PINK1-mediated mitophagy induction alleviates sodium fluoride-induced hepatic injury by improving mitochondrial function, oxidative stress, and …
C Song, A Zhang, M Zhang, Y Song, H Huangfu… - Ecotoxicology and …, 2023 - Elsevier
Mitophagy has distinct functions, which can lead to either protection or damage of tissues.
Though current evidence indicated that NaF triggers mitophagy, the role and regulation of …
Though current evidence indicated that NaF triggers mitophagy, the role and regulation of …
[HTML][HTML] Integrative transcriptome and metabolome analysis of fluoride exposure induced developmental neurotoxicity in mouse brain
X Zhu, S Zhang, X Liu, H Li, X Zhu, J Zhang… - Ecotoxicology and …, 2024 - Elsevier
Fluoride could cause developmental neurotoxicity and significantly affect the intelligence
quotient (IQ) of children. However, the systematic mechanism of neuronal damage caused …
quotient (IQ) of children. However, the systematic mechanism of neuronal damage caused …
[HTML][HTML] Metabolic effect of low fluoride levels in the islets of NOD mice: integrative morphological, immunohistochemical, and proteomic analyses
JS Trevizol, A Dionizio, AQ Delgado… - Journal of Applied Oral …, 2023 - SciELO Brasil
Fluoride (F) has been widely used to control dental caries, and studies suggest beneficial
effects against diabetes when a low dose of F is added to the drinking water (10 mgF/L) …
effects against diabetes when a low dose of F is added to the drinking water (10 mgF/L) …