Common features of microRNA target prediction tools

SM Peterson, JA Thompson, ML Ufkin… - Frontiers in …, 2014 - frontiersin.org
The human genome encodes for over 1800 microRNAs (miRNAs), which are short non-
coding RNA molecules that function to regulate gene expression post-transcriptionally. Due …

Bioinformatic tools for microRNA dissection

MM Akhtar, L Micolucci, MS Islam, F Olivieri… - Nucleic acids …, 2016 - academic.oup.com
Recently, microRNAs (miRNAs) have emerged as important elements of gene regulatory
networks. MiRNAs are endogenous single-stranded non-coding RNAs (∼ 22-nt long) that …

miRNASNP-v3: a comprehensive database for SNPs and disease-related variations in miRNAs and miRNA targets

CJ Liu, X Fu, M Xia, Q Zhang, Z Gu… - Nucleic acids …, 2021 - academic.oup.com
MicroRNAs (miRNAs) related single-nucleotide variations (SNVs), including single-
nucleotide polymorphisms (SNPs) and disease-related variations (DRVs) in miRNAs and …

MirDIP 5.2: tissue context annotation and novel microRNA curation

AC Hauschild, C Pastrello, GKA Ekaputeri… - Nucleic Acids …, 2023 - academic.oup.com
MirDIP is a well-established database that aggregates microRNA-gene human interactions
from multiple databases to increase coverage, reduce bias, and improve usability by …

Long noncoding RNA UCA1 from hypoxia-conditioned hMSC-derived exosomes: a novel molecular target for cardioprotection through miR-873-5p/XIAP axis

L Sun, W Zhu, P Zhao, Q Wang, B Fan, Y Zhu… - Cell death & …, 2020 - nature.com
Exosomes (Exo) secreted from mesenchymal stem cells (hMSCs) are protective against
myocardial injury. The purpose of the study was to investigate the role and mechanisms by …

TarPmiR: a new approach for microRNA target site prediction

J Ding, X Li, H Hu - Bioinformatics, 2016 - academic.oup.com
Motivation: The identification of microRNA (miRNA) target sites is fundamentally important
for studying gene regulation. There are dozens of computational methods available for …

Cellular miR-150-5p may have a crucial role to play in the biology of SARS-CoV-2 infection by regulating nsp10 gene

SM Akula, P Bolin, PP Cook - RNA biology, 2022 - Taylor & Francis
The role for circulating miRNAs as biomarkers of the COVID-19 disease remains uncertain.
We analysed the circulating miRNA profile in twelve COVID-19 patients with moderate …

Towards realizing the vision of precision medicine: AI based prediction of clinical drug response

J de Jong, I Cutcutache, M Page, S Elmoufti, C Dilley… - Brain, 2021 - academic.oup.com
Accurate and individualized prediction of response to therapies is central to precision
medicine. However, because of the generally complex and multifaceted nature of clinical …

A positive role of microRNA‐15b on regulation of osteoblast differentiation

S Vimalraj, NC Partridge… - Journal of cellular …, 2014 - Wiley Online Library
Osteoblast differentiation is tightly regulated by several factors including microRNAs
(miRNAs). In this paper, we report that pre‐mir‐15b is highly expressed in differentiated …

miRAW: A deep learning-based approach to predict microRNA targets by analyzing whole microRNA transcripts

A Pla, X Zhong, S Rayner - PLoS computational biology, 2018 - journals.plos.org
MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression by binding
to partially complementary regions within the 3'UTR of their target genes. Computational …