Fabrication of biomedical scaffolds using biodegradable polymers

A Kirillova, TR Yeazel, D Asheghali… - Chemical …, 2021 - ACS Publications
Degradable polymers are used widely in tissue engineering and regenerative medicine.
Maturing capabilities in additive manufacturing coupled with advances in orthogonal …

Biopolymeric nanocomposite scaffolds for bone tissue engineering applications–A review

PN Christy, SK Basha, VS Kumari, AKH Bashir… - Journal of drug delivery …, 2020 - Elsevier
Tissue engineering is the immense area of research in recent years because of its vast
potential in the repair or replacement of impaired tissues and organs. Bone is a …

[HTML][HTML] Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly (ε-caprolactone)/nano …

X Ji, X Yuan, L Ma, B Bi, H Zhu, Z Lei, W Liu, HX Pu… - Theranostics, 2020 - ncbi.nlm.nih.gov
Chitin-derived hydrogels are commonly used in bone regeneration because of their high cell
compatibility; however, their poor mechanical properties and little knowledge of the …

[HTML][HTML] 3D biodegradable scaffolds of polycaprolactone with silicate-containing hydroxyapatite microparticles for bone tissue engineering: High-resolution …

S Shkarina, R Shkarin, V Weinhardt, E Melnik… - Scientific reports, 2018 - nature.com
To date, special interest has been paid to composite scaffolds based on polymers enriched
with hydroxyapatite (HA). However, the role of HA containing different trace elements such …

Multi-layered polydopamine coatings for the immobilization of growth factors onto highly-interconnected and bimodal PCL/HA-based scaffolds

M Godoy-Gallardo, N Portoles-Gil… - Materials Science and …, 2020 - Elsevier
For bone tissue engineering applications, scaffolds that mimic the porous structure of the
extracellular matrix are highly desirable. Herein, we employ a PCL/HA-based scaffold with a …

Fabrication and biological activity of 3D-printed polycaprolactone/magnesium porous scaffolds for critical size bone defect repair

S Zhao, K Xie, Y Guo, J Tan, J Wu, Y Yang… - ACS Biomaterials …, 2020 - ACS Publications
Polycaprolactone (PCL) is widely used in bone tissue engineering due to its biocompatibility
and mechanical strength. However, PCL is not biologically active and shows poor …

Assessments of polycaprolactone/hydroxyapatite composite scaffold with enhanced biomimetic mineralization by exposure to hydroxyapatite via a 3D-printing system …

YS Cho, S Choi, SH Lee, KK Kim, YS Cho - European Polymer Journal, 2019 - Elsevier
In the 3D-printed polycaprolactone/hydroxyapatite composite scaffold, hydroxyapatite
particles are usually covered by a thin-film of polycaprolactone because of the rheological …

[HTML][HTML] Immobilization of BMP-2 and VEGF within multilayered polydopamine-coated scaffolds and the resulting osteogenic and angiogenic synergy of co-cultured …

M Godoy-Gallardo, N Portolés-Gil… - International Journal of …, 2020 - mdpi.com
We have previously reported the fabrication of a polycaprolactone and hydroxyapatite
composite scaffold incorporating growth factors to be used for bone regeneration. Two …

In vitro degradation behaviour of hybrid electrospun scaffolds of polycaprolactone and strontium-containing hydroxyapatite microparticles

EV Melnik, SN Shkarina, SI Ivlev, V Weinhardt… - … degradation and stability, 2019 - Elsevier
We investigated the effect of varying content Sr-containing HA (SrHA) microparticles on the
in vitro degradation of polycaprolactone (PCL) hybrid scaffolds. A degradation behaviour …

Magnesium ions enhance infiltration of osteoblasts in scaffolds via increasing cell motility

KJ Kim, S Choi, Y Sang Cho, SJ Yang, YS Cho… - Journal of Materials …, 2017 - Springer
Magnesium (Mg) ions are the most abundant intracellular divalent cations and play a pivotal
role in numerous cellular processes. Biodegradable Mg-containing materials, including …