Biosynthesis and synthetic biology of psychoactive natural products
Psychoactive natural products play an integral role in the modern world. The tremendous
structural complexity displayed by such molecules confers diverse biological activities of …
structural complexity displayed by such molecules confers diverse biological activities of …
Dark classics in chemical neuroscience: mescaline
BK Cassels, P Sáez-Briones - ACS chemical neuroscience, 2018 - ACS Publications
Archeological studies in the United States, Mexico, and Peru suggest that mescaline, as a
cactus constituent, has been used for more than 6000 years. Although it is a widespread …
cactus constituent, has been used for more than 6000 years. Although it is a widespread …
Relaxation of tyrosine pathway regulation underlies the evolution of betalain pigmentation in Caryophyllales
Diverse natural products are synthesized in plants by specialized metabolic enzymes, which
are often lineage‐specific and derived from gene duplication followed by functional …
are often lineage‐specific and derived from gene duplication followed by functional …
Elucidation of the mescaline biosynthetic pathway in peyote (Lophophora williamsii)
JL Watkins, Q Li, S Yeaman, PJ Facchini - The Plant Journal, 2023 - Wiley Online Library
Peyote (Lophophora williamsii) is an entheogenic and medicinal cactus native to the
Chihuahuan desert. The psychoactive and hallucinogenic properties of peyote are …
Chihuahuan desert. The psychoactive and hallucinogenic properties of peyote are …
An overview on the hallucinogenic peyote and its alkaloid mescaline: The importance of context, ceremony and culture
M Doesburg-van Kleffens, AM Zimmermann-Klemd… - Molecules, 2023 - mdpi.com
Peyote (Lophophora williamsii) is a cactus that contains various biologically active alkaloids—
such as pellotine, anhalonidine, hordenine and mescaline. Here, mescaline induces the …
such as pellotine, anhalonidine, hordenine and mescaline. Here, mescaline induces the …
Emerging model systems for functional genomics analysis of Crassulacean acid metabolism
J Hartwell, LV Dever, SF Boxall - Current Opinion in Plant Biology, 2016 - Elsevier
Highlights•Efforts are now underway to decipher the genetic blueprint for CAM.•Several
CAM genomes and transcriptomes have recently been published.•Kalanchoë has been …
CAM genomes and transcriptomes have recently been published.•Kalanchoë has been …
The biosynthetic pathway of the hallucinogen mescaline and its heterologous reconstruction
Mescaline, among the earliest identified natural hallucinogens, holds great potential in
psychotherapy treatment. Nonetheless, despite the existence of a postulated biosynthetic …
psychotherapy treatment. Nonetheless, despite the existence of a postulated biosynthetic …
Transcriptomics insights into the genetic regulation of root apical meristem exhaustion and determinate primary root growth in Pachycereus pringlei (Cactaceae)
G Rodriguez-Alonso, M Matvienko, ML López-Valle… - Scientific Reports, 2018 - nature.com
Many Cactaceae species exhibit determinate growth of the primary root as a consequence
of root apical meristem (RAM) exhaustion. The genetic regulation of this growth pattern is …
of root apical meristem (RAM) exhaustion. The genetic regulation of this growth pattern is …
The Alkaloids from Lophophora diffusa and Other “False Peyotes”
CB Chan, CBM Poulie, SS Wismann… - Journal of Natural …, 2021 - ACS Publications
Commonly, false peyote refers to Lophophora diffusa. However, several other unrelated
cacti go by this colloquial name. They either resemble “true” peyote, Lophophora williamsii …
cacti go by this colloquial name. They either resemble “true” peyote, Lophophora williamsii …
L-DOPA and dopamine in plant metabolism
R Marchiosi, AR Soares, J Abrahão… - … in plant signaling and …, 2020 - Springer
Nonprotein amino acids are widely distributed in the plants. They constitute a numerous
group of secondary metabolites and represent a relevant reservoir of nitrogen and carbon …
group of secondary metabolites and represent a relevant reservoir of nitrogen and carbon …