[HTML][HTML] The roles of ZEB1 in tumorigenic progression and epigenetic modifications

Y Zhang, L Xu, A Li, X Han - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Highly expressed Zinc-finger E-box binding protein 1 (ZEB1) is significantly associated with
the malignancy of various cancers. Signal transduction and activation of ZEB1 play …

[HTML][HTML] Epithelial-mesenchymal transition in prostate cancer: an overview

M Montanari, S Rossetti, C Cavaliere, C D'Aniello… - Oncotarget, 2017 - ncbi.nlm.nih.gov
Prostate cancer is a main urological disease associated with significant morbidity and
mortality. Radical prostatectomy and radiotherapy are potentially curative for localized …

LncRNA KCNQ1OT1 regulates proliferation and cisplatin resistance in tongue cancer via miR-211-5p mediated Ezrin/Fak/Src signaling

S Zhang, H Ma, D Zhang, S Xie, W Wang, Q Li… - Cell death & …, 2018 - nature.com
Numerous findings have demonstrated that long noncoding RNA (lncRNA) dysregulation
plays a key role in many human neoplasms, including tongue squamous cell carcinoma …

Long non coding RNA MALAT1 promotes tumor growth and metastasis by inducing epithelial-mesenchymal transition in oral squamous cell carcinoma

X Zhou, S Liu, G Cai, L Kong, T Zhang, Y Ren, Y Wu… - Scientific reports, 2015 - nature.com
The prognosis of advanced oral squamous cell carcinoma (OSCC) patients remains dismal
and a better understanding of the underlying mechanisms is critical for identifying effective …

[HTML][HTML] Cancer-associated Fibroblasts induce epithelial-mesenchymal transition via the Transglutaminase 2-dependent IL-6/IL6R/STAT3 axis in Hepatocellular …

C Jia, G Wang, T Wang, B Fu, Y Zhang… - … journal of biological …, 2020 - ncbi.nlm.nih.gov
Cancer-associated fibroblasts (CAFs) play crucial roles in enhancing cell survival,
proliferation, invasion, and metastasis. We previously showed that hepatocellular carcinoma …

Pathophysiological roles of actin-binding scaffold protein, ezrin

K Kawaguchi, S Asano - International journal of molecular sciences, 2022 - mdpi.com
Ezrin is one of the members of the ezrin/radixin/moesin (ERM) family of proteins. It was
originally discovered as an actin-binding protein in the microvilli structure about forty years …

Inflammatory mediators in oral cancer: pathogenic mechanisms and diagnostic potential

SE Niklander - Frontiers in Oral Health, 2021 - frontiersin.org
Approximately 15% of cancers are attributable to the inflammatory process, and growing
evidence supports an association between oral squamous cell carcinoma (OSCC) and …

The role of the ZEB1–neuroinflammation axis in CNS disorders

E Poonaki, UD Kahlert, SG Meuth, A Gorji - Journal of Neuroinflammation, 2022 - Springer
Zinc finger E-box binding homeobox 1 (ZEB1) is a master modulator of the epithelial–
mesenchymal transition (EMT), a process whereby epithelial cells undergo a series of …

EGF induces epithelial-mesenchymal transition and cancer stem-like cell properties in human oral cancer cells via promoting Warburg effect

Q Xu, Q Zhang, Y Ishida, S Hajjar, X Tang, H Shi… - …, 2016 - pmc.ncbi.nlm.nih.gov
“Warburg effect”, the enhanced glycolysis or aerobic glycolysis, confers cancer cells the
ability to survive and proliferate even under stressed conditions. In this study, we explored …

[HTML][HTML] HOTAIR is a therapeutic target in glioblastoma

X Zhou, Y Ren, J Zhang, C Zhang, K Zhang, L Han… - Oncotarget, 2015 - ncbi.nlm.nih.gov
HOTAIR is a negative prognostic factor and is overexpressed in multiple human cancers
including glioblastoma multiform (GBM). Survival analysis of Chinese Glioma Genome Atlas …