Plant molecular farming (PMF) has been promoted as a fast, efficient and cost-effective
alternative to bacteria and animal cells for the production of biopharmaceutical proteins …

Drug repurposing in glomerular disease can deliver opportunities for steroid-free regimens,
enable personalized multi-target options for resistant or relapsing disease and enhance …

Abstract Objectives Clinical study reports (CSRs) are highly detailed documents that play a
pivotal role in medicine approval processes. Though not historically publicly available, in …

Abstracts Objective Data sharing statements are considered routine in clinical trial reporting,
and represent a step towards data transparency. The International Committee of Medical …

Background Due to increasing life expectancy, almost half of people with type 2 diabetes are
aged 65 years or over worldwide. When metformin alone does not control blood sugar, the …

Background Amid growing emphasis from pharmaceutical companies, advocacy groups,
and regulatory bodies for sharing of individual participant data, recent audits reveal limited …

Unlocking the full potential of clinical trials through comprehensive CSR and IPD sharing
can revolutionize cancer care, enhance safety evaluations, and reduce bias in systematic …

Background: The promotion of the latest medicines produced by the pharmaceutical industry
is an important issue both from an ethical point of view (the level of accessibility, the way …

In Reply We thank Zhang and colleagues for their appraisal of our work. 1 Regarding the
first point, it appears that the authors have misinterpreted our statistical analysis. The authors …

Methods: PCS cases or controls were invited for a comprehensive outpatient clinical
assessment. PCS cases were defined as no more than 80% recovery of general health or …