As germline genetic testing capacities have improved over the last two decades,
increasingly more people are newly diagnosed with germline cancer susceptibility …

The safety and efficacy of pharmacotherapy in children, particularly preterms, neonates and
infants, is limited by a paucity of good‐quality data from prospective clinical drug trials. A …

Pediatric cancer outcomes have significantly improved, and yet this success is not spread
equally across cancer types or patients. Disparities data in pediatric oncology highlight …

Clinical trials conducted by the Intergroup Rhabdomyosarcoma (RMS) Study Group and the
Children's Oncology Group have been pivotal to establishing current standards for diagnosis …

ABSTRACT Introduction Drug hypersensitivity reactions (DHRs) represent a great challenge
to clinicians due to their unpredictability and severity, notably being potentially fatal. Genetic …

Drug use in children is–in most cases–supported by extrapolation of data generated from
clinical trials in adult populations. This puts children at higher risk of developing adverse …

Precision Medicine is an approach to disease treatment and prevention taking into account
individual genetic, environmental, therapeutic and lifestyle variability for each person. This …

Importance of pharmacologic considerations in the developmen... : Current Opinion in Pediatrics
Importance of pharmacologic considerations in the development of targeted anticancer agents …

The interaction of pediatricians with pediatric oncologists is important for the optimization
and treatment of children suffering from oncological diseases. Modern practice strives for a …

Введение. На сегодняшний день возрастает актуальность вопросов ранней и
отдаленной токсичности противоопухолевой терапии, особенно у пациентов детского …