Idiopathic intracranial hypertension: a step change in understanding the disease mechanisms

A Yiangou, SP Mollan, AJ Sinclair - Nature Reviews Neurology, 2023 - nature.com
The understanding of idiopathic intracranial hypertension (IIH) has evolved over the past few
years. Previously, IIH was considered a disease exclusively affecting the neuro-ophthalmic …

“Idiopathic” intracranial hypertension: An update from neurointerventional research for clinicians

KM Fargen, S Coffman, T Torosian, W Brinjikji… - …, 2023 - journals.sagepub.com
Background The recognition of venous sinus stenosis as a contributing factor in the majority
of patients with idiopathic intracranial hypertension coupled with increasing cerebral …

The effect of GLP-1RA exenatide on idiopathic intracranial hypertension: a randomized clinical trial

JL Mitchell, HS Lyons, JK Walker, A Yiangou, O Grech… - Brain, 2023 - academic.oup.com
Therapeutics to reduce intracranial pressure are an unmet need. Preclinical data have
demonstrated a novel strategy to lower intracranial pressure using glucagon-like peptide-1 …

The idiopathic intracranial hypertension prospective cohort study: evaluation of prognostic factors and outcomes

M Thaller, V Homer, Y Hyder, A Yiangou… - Journal of …, 2023 - Springer
Background There are limited longitudinal data evaluating outcomes in idiopathic
intracranial hypertension (IIH). We aimed to evaluate the long-term outcomes in a real-world …

Association of amount of weight lost after bariatric surgery with intracranial pressure in women with idiopathic intracranial hypertension

SP Mollan, JL Mitchell, A Yiangou, RS Ottridge… - Neurology, 2022 - AAN Enterprises
Background and Objectives The idiopathic intracranial hypertension randomized controlled
weight trial (IIH: WT) established that weight loss through bariatric surgery significantly …

Weight management interventions for adults with idiopathic intracranial hypertension: a systematic review and practice recommendations

S Abbott, F Chan, AA Tahrani, SH Wong… - Neurology, 2023 - AAN Enterprises
Background and Objectives Idiopathic intracranial hypertension (IIH) is associated with
obesity; however, there is a lack of clinical consensus on how to manage weight in IIH. The …

Managing idiopathic intracranial hypertension in pregnancy: practical advice

M Thaller, BR Wakerley, S Abbott, AA Tahrani… - Practical …, 2022 - pn.bmj.com
Idiopathic intracranial hypertension (IIH) is more common in women of reproductive age who
have obesity, yet there is little information on its management specifically in pregnancy …

The role of obesity and bariatric surgery-induced weight loss in breast cancer

MS Bohm, LM Sipe, ME Pye, MJ Davis… - Cancer and Metastasis …, 2022 - Springer
Obesity is a complex metabolic condition considered a worldwide public health crisis, and a
deeper mechanistic understanding of obesity-associated diseases is urgently needed …

Bariatric surgery for patients with overweight/obesity. A comprehensive grading methodology and network metanalysis of randomized controlled trials on weight loss …

M De Luca, M Zese, GA Silverii, B Ragghianti… - Obesity Surgery, 2023 - Springer
This study aims to compare different types of metabolic bariatric surgery (MBS) with lifestyle
intervention/medical therapy (LSI/MT) for the treatment of overweight/obesity. The present …

[HTML][HTML] Defining the phenotype and prognosis of people with idiopathic intracranial hypertension after cerebrospinal fluid diversion surgery

YF Hyder, V Homer, M Thaller, M Byrne… - American Journal of …, 2023 - Elsevier
Purpose To characterize the phenotype of patients with idiopathic intracranial hypertension
(IIH) who received cerebrospinal (CSF) diversion surgery and to detail the trajectory of …