As the world endures the coronavirus disease 2019 (COVID-19) pandemic, the conditions of
35 million vulnerable individuals struggling with substance use disorders (SUDs) worldwide …

Background The use of cannabis, or marijuana, for medicinal purposes is deeply rooted
though history, dating back to ancient times. It once held a prominent position in the history …

Objectives: This meta-analysis examines the strength of the link between substance use (eg,
alcohol use vs. drug use) and intimate partner violence (IPV) perpetration and victimization …

Nicotine stimulates the dopamine (DA) system, which is essential for its rewarding effect.
Nicotine is also aversive at high doses; yet, our knowledge about nicotine's dose-dependent …

Drug use represents a significant burden to public health through disease, disability and
social problems, and policy makers are becoming increasingly interested in how to develop …

Background/Aim: The aim of the current study was to review drug harms as they occur in
Australia using the Multi-criteria Decision Analysis (MCDA) methodology adopted in earlier …

EXECUTIVE SUMMARY In November 2012, Colorado and Washington approved ballot
initiatives that legalized marijuana for recreational use under state law. Since then, nine …

The consumption of alcoholic beverages has been classified as carcinogenic to humans by
the International Agency for Research on Cancer (IARC) since 1988. More recently, in 2010 …

Background With impending marijuana legislation in Canada, a broad understanding of the
harms associated with marijuana use is needed to inform the clinical community and public …

Trigonelline is a bioactive pyridine alkaloid that occurs naturally in high concentrations in
coffee (up to 7.2 g/kg) and coffee by-products (up to 62.6 g/kg) such as coffee leaves …