Mechanical stress from haemodynamic perturbations or interventional manipulation of
epicardial coronary atherosclerotic plaques with inflammatory destabilization can release …

Cardioprotection aims at infarct size reduction and improvement of clinical outcome from
myocardial infarction. The translation of cardioprotection from preclinical and promising …

Primary percutaneous coronary intervention is nowadays the preferred reperfusion strategy
for patients with acute ST-segment–elevation myocardial infarction, aiming at restoring …

Early mechanical reperfusion of the epicardial coronary artery by primary percutaneous
coronary intervention (PCI) is the guideline-recommended treatment for ST-elevation …

Primary percutaneous angioplasty (pPCI), represents the reperfusion strategy of choice for
patients with STEMI according to current international guidelines of the European Society of …

Myocardial ischemia-reperfusion (MIR) injury is a major cause of adverse outcomes of
revascularization after myocardial infarction. To identify the fundamental regulator of …

Background: Patients with left ventricular (LV) systolic dysfunction after myocardial infarction
are at a high risk of developing heart failure. The addition of neprilysin inhibition to renin …

Cardiac MRI is a noninvasive diagnostic tool using nonionizing radiation that is widely used
in patients with ST-segment elevation myocardial infarction (STEMI). Cardiac MRI depicts …

Successful reperfusion of an infarct-related coronary artery by primary percutaneous
intervention or fibrinolysis during acute ST-elevation myocardial infarction (STEMI) does not …

Despite prompt epicardial recanalization in patients presenting with ST-segment elevation
myocardial infarction (STEMI), coronary microvascular obstruction and dysfunction (CMVO) …