Breast cancer lung metastasis: Molecular biology and therapeutic implications

L Jin, B Han, E Siegel, Y Cui, A Giuliano… - Cancer biology & …, 2018 - Taylor & Francis
Distant metastasis accounts for the vast majority of deaths in patients with cancer. Breast
cancer exhibits a distinct metastatic pattern commonly involving bone, liver, lung, and brain …

[HTML][HTML] Polysaccharide-based nanomedicines for cancer immunotherapy: A review

Y Zeng, Y Xiang, R Sheng, H Tomás, J Rodrigues… - Bioactive Materials, 2021 - Elsevier
Cancer immunotherapy is an effective antitumor approach through activating immune
systems to eradicate tumors by immunotherapeutics. However, direct administration of …

A population-level digital histologic biomarker for enhanced prognosis of invasive breast cancer

M Amgad, JM Hodge, MAT Elsebaie, C Bodelon… - Nature Medicine, 2024 - nature.com
Breast cancer is a heterogeneous disease with variable survival outcomes. Pathologists
grade the microscopic appearance of breast tissue using the Nottingham criteria, which are …

Advanced approaches to breast cancer classification and diagnosis

M Zubair, S Wang, N Ali - Frontiers in Pharmacology, 2021 - frontiersin.org
The International Agency for Research on Cancer (IARC) has recently reported a 66%
increase in the global number of cancer deaths since 1960. In the US alone, about one in …

In vivo models in breast cancer research: progress, challenges and future directions

I Holen, V Speirs, B Morrissey… - Disease models & …, 2017 - journals.biologists.com
Research using animal model systems has been instrumental in delivering improved
therapies for breast cancer, as well as in generating new insights into the mechanisms that …

Tumor microenvironment: key players in triple negative breast cancer immunomodulation

H Zheng, S Siddharth, S Parida, X Wu, D Sharma - Cancers, 2021 - mdpi.com
Simple Summary The tumor microenvironment (TME) is a complicated network composed of
various cells, signaling molecules, and extra cellular matrix. TME plays a crucial role in triple …

Molecular links between central obesity and breast cancer

AA Zimta, AB Tigu, M Muntean, D Cenariu… - International journal of …, 2019 - mdpi.com
Worldwide, breast cancer (BC) is the most common malignancy in women, in regard to
incidence and mortality. In recent years, the negative role of obesity during BC development …

Immunotherapy for HER2-positive breast cancer: recent advances and combination therapeutic approaches

NM Ayoub, KM Al-Shami, RJ Yaghan - Breast Cancer: Targets and …, 2019 - Taylor & Francis
Cancer immunotherapy has evolved dramatically with improved understanding of immune
microenvironment and immunosurveillance. The immunogenicity of breast cancer is rather …

3D cancer models: Depicting cellular crosstalk within the tumour microenvironment

T Franchi-Mendes, R Eduardo, G Domenici, C Brito - Cancers, 2021 - mdpi.com
Simple Summary The tumour microenvironment is composed of multiple non-cancerous
cells that communicate with the tumour cells, influencing their behaviour and impacting the …

High expression of microRNA-143 is associated with favorable tumor immune microenvironment and better survival in estrogen receptor positive breast cancer

Y Tokumaru, M Asaoka, M Oshi, E Katsuta… - International journal of …, 2020 - mdpi.com
microRNA-143 (miR-143) is a well-known tumor suppressive microRNA that exhibits anti-
tumoral function by targeting KRAS signaling pathways in various malignancies. We …