Lung cancer is a major cause of cancer deaths worldwide, and has a very low survival rate.
Non-small cell lung cancer (NSCLC) is the largest subset of lung cancers, which accounts …

Klebsiella pneumoniae is a hospital-acquired pathogen that leads to various infections.
There is a great interest in developing an efficient Klebsiella vaccine and epitope-based …

Abstract Single-nucleotide polymorphisms (SNPs), a most common type of genetic
mutations, result from single base pair alterations. Non-synonymous SNPs (nsSNP) occur in …

Parkinson's disease (PD) is a multifactorial ailment that severely affects the viability of
dopaminergic neurons leading to progressive loss of motor control. The current regimen for …

In order to improve manganese-SOD stability, three mutations were constructed via site-
directed mutagenesis, and the root mean square fluctuation (RMSF) and root mean square …

The rapid appearance of resistant malarial parasites after introduction of atovaquone (ATQ)
drug has prompted the search for new drugs as even single point mutations in the active site …

Aquaporins comprise a large group of transmembrane proteins responsible for water
transport, which is crucial for plant survival under stress conditions. Despite the vital role of …

Mutations in the retinal inosine monophosphate dehydrogenase1 (IMPDH1) gene is
believed to be one cause of retinitis pigmentosa (RP). The main structural difference …

Infectious diseases are an important cause of fatality worldwide and administration of
vaccines could provide long-lasting protection against responsible infection. Incorporating of …

Salmonella enterica is an important enteric pathogen that causes intestinal and systemic
infections in warm-blooded animals. Due to different problems caused by administration of …