Recent developments in aptasensors for diagnostic applications

LS Liu, F Wang, Y Ge, PK Lo - ACS Applied Materials & Interfaces, 2020 - ACS Publications
Aptamers are exciting smart molecular probes for specific recognition of disease biomarkers.
A number of strategies have been developed to convert target–aptamer binding into …

Electrochemical aptasensors–recent achievements and perspectives

T Hianik, J Wang - … to Fundamental and Practical Aspects of …, 2009 - Wiley Online Library
This article reviews recent achievements in developing aptamer‐based electrochemical
biosensors (electrochemical aptasensors). Aptamers are single stranded DNA or RNA …

Protein detection by nanopores equipped with aptamers

D Rotem, L Jayasinghe, M Salichou… - Journal of the American …, 2012 - ACS Publications
Protein nanopores have been used as stochastic sensors for the detection of analytes that
range from small molecules to proteins. In this approach, individual analyte molecules …

Applications of aptasensors in clinical diagnostics

P Hong, W Li, J Li - Sensors, 2012 - mdpi.com
Aptamers are artificial oligonucleotides (DNA or RNA) selected in vitro that bind a broad
range of targets with high affinity and specificity; a sensitive yet simple method to utilize …

Nucleic acid aptamers for biosensors and bio-analytical applications

K Sefah, JA Phillips, X Xiong, L Meng, D Van Simaeys… - Analyst, 2009 - pubs.rsc.org
Oligonucleotides were once considered only functional as molecules for the storage of
genetic information. However, the discovery of RNAzymes, and later, DNAzymes, unravelled …

In situ biosensing with a surface plasmon resonance fiber grating aptasensor

Y Shevchenko, TJ Francis, DAD Blair, R Walsh… - Analytical …, 2011 - ACS Publications
Surface plasmon resonance (SPR) biosensors prepared using optical fibers can be used as
a cost-effective and relatively simple-to-implement alternative to well established biosensor …

Voltammetric aptasensors for protein disease biomarkers detection: A review

SG Meirinho, LG Dias, AM Peres, LR Rodrigues - Biotechnology advances, 2016 - Elsevier
An electrochemical aptasensor is a compact analytical device where the bioreceptor
(aptamer) is coupled to a transducer surface to convert a biological interaction into a …

Selection of aptamers against live bacterial cells

CLA Hamula, H Zhang, LL Guan, XF Li… - Analytical …, 2008 - ACS Publications
Single-stranded DNA or RNA aptamer molecules have usually been selected against
purified target molecules. To eliminate the need of purifying target molecules on the cell …

Aptamers targeting membrane proteins for sensor and diagnostic applications

N Kara, N Ayoub, H Ilgu, D Fotiadis, M Ilgu - Molecules, 2023 - mdpi.com
Many biological processes (physiological or pathological) are relevant to membrane
proteins (MPs), which account for almost 30% of the total of human proteins. As such, MPs …

Aptasensors: a review

YC Lim, AZ Kouzani, W Duan - Journal of biomedical …, 2010 - ingentaconnect.com
Aptamers are a promising class of agents for biomolecules detection due to their small size,
chemical stability and cost effectiveness over conventional bioreceptors such as antibodies …