Tumor recurrences or metastases remain a major hurdle in improving overall cancer
survival. In the perioperative period, the balance between the ability of the cancer to seed …

Purpose Cancer-related mortality, a leading cause of death worldwide, is often the result of
metastatic disease recurrence. Anesthetic techniques have varying effects on innate and …

Background microRNAs (miRNAs) are single-stranded and noncoding RNA molecules that
control post-transcriptional gene regulation. miRNAs can be tumor suppressors or …

The majority of ovarian cancer patients relapse after surgical resection. Evidence is
accumulating regarding the role of surgery in disseminating cancer cells; in particular …

Propofol is a widely used intravenous anesthetic agent with potential neuroprotective effect
in diverse models of neuronal injury, including ischemic stroke and traumatic brain injury …

Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

Oncological surgery and anesthesia both stimulate the hypothalamic-pituitary-adrenal (HPA)
axis and the sympathetic nervous system (SNS). The HPA axis suppresses the host immune …

Cancer cell migration and invasion are essential features of the metastatic process. Volatile
anesthetic sevoflurane inhibits the migration and invasion of multiple cancer cell lines; …

Background: MicroRNAs participate in the regulation of numerous physiological and
disease processes. The in vivo role of microRNAs in anesthetics-conferred organoprotection …

Sevoflurane is the most widely used anaesthetic administered by inhalation. Exposure to
sevoflurane in neonatal mice can induce learning deficits and abnormal social behaviours …