Laboratory diagnosis of cutaneous and visceral leishmaniasis: current and future methods

JQ Reimão, EM Coser, MR Lee, AC Coelho - Microorganisms, 2020 - mdpi.com
Leishmaniasis is a neglected tropical disease with two main clinical forms: cutaneous and
visceral leishmaniasis. Diagnosis of leishmaniasis is still a challenge, concerning the …

Recent updates and perspectives on approaches for the development of vaccines against visceral leishmaniasis

MC Duarte, DP Lage, VT Martins… - Revista da Sociedade …, 2016 - SciELO Brasil
Visceral leishmaniasis (VL) is one of the most important tropical diseases worldwide.
Although chemotherapy has been widely used to treat this disease, problems related to the …

[HTML][HTML] Proteomic analysis of exosomes derived from procyclic and metacyclic-like cultured Leishmania infantum chagasi

DM Forrest, M Batista, FK Marchini, AJ Tempone… - Journal of …, 2020 - Elsevier
Leishmania infantum chagasi is the primary etiological agent of visceral leishmaniasis in
Latin America, a lethal disease that afflicts hundreds of thousands of people worldwide …

A candidate vaccine for human visceral leishmaniasis based on a specific T cell epitope-containing chimeric protein protects mice against Leishmania infantum …

DP Lage, PAF Ribeiro, DS Dias, DVC Mendonça… - npj Vaccines, 2020 - nature.com
Leishmaniases are neglected diseases caused by infection with Leishmania parasites and
there are currently no prophylactic vaccines. In this study, we designed in silico a synthetic …

Nanomedicine in leishmaniasis: A promising tool for diagnosis, treatment and prevention of disease-An update overview

JP Assolini, ACM Carloto, BT da Silva Bortoleti… - European Journal of …, 2022 - Elsevier
Leishmaniasis is a neglected tropical disease that has a wide spectrum of clinical
manifestations, ranging from visceral to cutaneous, with millions of new cases and …

Antileishmanial Activity, Cytotoxicity and Mechanism of Action of Clioquinol Against Leishmania infantum and Leishmania amazonensis Species

GSV Tavares, DVC Mendonça, DP Lage… - Basic & Clinical …, 2018 - Wiley Online Library
In this study, a quinoline derivate, clioquinol (5‐chloro‐7‐iodoquinolin‐8‐ol), was evaluated
against Leishmania amazonensis and Leishmania infantum promastigotes and amastigotes …

Understanding Leishmania parasites through proteomics and implications for the clinic

S Sundar, B Singh - Expert review of proteomics, 2018 - Taylor & Francis
Introduction: Leishmania spp. are causative agents of leishmaniasis, a broad-spectrum
neglected vector-borne disease. Genomic and transcriptional studies are not capable of …

Potential antigenic targets used in immunological tests for diagnosis of tegumentary leishmaniasis: A systematic review

ML Freire, FD Rêgo, G Cota, MA Pascoal-Xavier… - PLoS …, 2021 - journals.plos.org
Immunological tests may represent valuable tools for the diagnosis of human tegumentary
leishmaniasis (TL) due to their simple execution, less invasive nature and potential use as a …

[HTML][HTML] Comparison of urine and serum IgG detection ELISA for tegumentary leishmaniasis diagnosis and prognosis

RSB Câmara, IAG Pereira, DP Lage, DL Vale, F Ludolf… - Immunobiology, 2024 - Elsevier
Laboratorial diagnosis of tegumentary leishmaniasis (TL) is hampered by variable sensitivity
and/or specificity of the tests, which are still hampered by blood́ invasive collection. In this …

Heat Mitigation Benefits of Urban Trees: A Review of Mechanisms, Modeling, Validation and Simulation

S Zheng, C He, JM Guldmann, H Xu, X Liu - Forests, 2023 - mdpi.com
Modeling, validating, and simulating are three essential parts in investigating the heat
mitigation benefits of urban trees (BUT). Therefore, 81 relevant studies from the last ten …