Glucocorticoid-induced leucine zipper (GILZ) is a protein with multiple biological roles that is
upregulated by glucocorticoids (GCs) in both immune and non-immune cells. Importantly …

Maladaptive insulin signaling is a key feature in the pathogenesis of severe metabolic
disorders, including obesity and diabetes. Enhancing insulin sensitivity represents a major …

Guishan goats, a unique goat breed in Yunnan Province, have a long history and
representation, but their whey protein and function remain unclear. In this study, we carried …

TSC-22 (TGF-β stimulated clone-22) has been reported to induce differentiation, growth
inhibition, and apoptosis in various cells. TSC-22 is a member of a family in which many …

Genome-wide association studies (GWAS) allow the identification of associations between
genetic variants and important phenotypes in domestic animals, including disease …

A major threat to gibel carp aquaculture is an epizootic disease caused by C. auratus
herpesvirus (CaHV). Therefore, breeding of disease resistant strain is one of significant …

Background TSC22D domain family genes, including TSC22D1-4, play a principal role in
cancer progression. However, their expression profiles and prognostic significance in adult …

Alcohol differentially affects human health, depending on the pattern of exposure. Moderate
intake provides beneficial mood modulation and an anti-inflammatory effect, while excessive …

One of the recent emerging global health issues is long COVID. Among long COVID
patients, long COVID-associated brain fog is an important area. We noted an immense gap …

Abstract Effect of exogenous transforming growth factor‑β1 (TGF‑β1) on cholestatic mice by
inhibiting Kupffer cell immune responses in liver was investigated. To induce cholestasis …