Fibrosis is defined as the abnormal and excessive deposition of extracellular matrix (ECM)
components, which leads to tissue or organ dysfunction and failure. However, the …

Objective Systemic sclerosis (SSc) is a multifactorial autoimmune fibrotic disorder involving
complex rewiring of cell‐intrinsic and cell‐extrinsic signaling coexpression networks …

Keratinocytes, the principal epidermal cells, play a vital role in maintaining the structural
integrity and functionality of the skin. Beyond their protective role, keratinocytes are key …

Diet High in salt content have been associated with cardiovascular disease and chronic
inflammation. We recently demonstrated that transient receptor potential canonical 3 …

The proinflammatory alarmins S100A8 and S100A9 are among the most abundant proteins
in neutrophils and monocytes but are completely silenced after differentiation to …

As the main constituent cells of the human placenta, trophoblasts proliferate, differentiate,
and invade the uterine endometrium via a series of processes, which are regulated …

Alzheimer's disease (AD) is the main cause of dementia, affecting the increasingly aging
population. Growing evidence indicates that neuro-inflammation plays crucial roles, eg, the …

Background Estrogen receptor (ER) positive human epidermal growth factor receptor 2
(HER2) negative breast cancer (ER+/HER2− BC) and triple-negative breast cancer (TNBC) …

Abstract Background/Aim Uremic cardiomyopathy (UCM) is a characteristic cardiac
pathology that is commonly found in patients with chronic kidney disease. This study …

Phycotoxins are responsible for foodborne intoxications. Symptoms depend on the ingested
toxins but mostly imply gastro-intestinal and neurological disorders. Importantly, humans are …