Maternal COVID-19 vaccination and its potential impact on fetal and neonatal development

NA Karrow, UK Shandilya, S Pelech… - Vaccines, 2021 - mdpi.com
Vaccines have been developed under accelerated timelines to combat the COVID-19
pandemic caused by the SARS-CoV-2 coronavirus. Although they are considered the best …

COVID-19 vaccine design using reverse and structural vaccinology, ontology-based literature mining and machine learning

A Huffman, E Ong, J Hur, A D'Mello… - Briefings in …, 2022 - academic.oup.com
Rational vaccine design, especially vaccine antigen identification and optimization, is critical
to successful and efficient vaccine development against various infectious diseases …

[HTML][HTML] Predicted structural mimicry of spike receptor-binding motifs from highly pathogenic human coronaviruses

CA Beaudoin, AR Jamasb, AF Alsulami… - Computational and …, 2021 - Elsevier
Viruses often encode proteins that mimic host proteins in order to facilitate infection. Little
work has been done to understand the potential mimicry of the SARS-CoV-2, SARS-CoV …

A deep integrated framework for predicting SARS-CoV2–human protein-protein interaction

S Ray, S Lall, S Bandyopadhyay - IEEE Transactions on …, 2022 - ieeexplore.ieee.org
Drug repurposing for COVID-19 is now an actively developing area of research.
Unavailability of a proper set of interactions between SARS-CoV2 and human host proteins …

Mining Autoimmune-Disorder-Linked Molecular-Mimicry Candidates in Clostridioides difficile and Prospects of Mimic-Based Vaccine Design: An In Silico Approach

S Alshamrani, MM Mashraqi, A Alzamami, NA Alturki… - Microorganisms, 2023 - mdpi.com
Molecular mimicry, a phenomenon in which microbial or environmental antigens resemble
host antigens, has been proposed as a potential trigger for autoimmune responses. In this …

In silico identification of potential inhibitors of the SARS-CoV-2 nucleocapsid through molecular docking-based drug repurposing

R Afreen, S Iqbal, H Afreen, L Vodwal… - Dr. Sulaiman Al Habib …, 2022 - journals.lww.com
SARS-CoV-2 is the virus responsible for the COVID-19 pandemic, and its effects on people
worldwide continue to grow. Protein-targeted therapeutics are currently unavailable for this …

The anti SARS-CoV-2 vaccines and the questions they raise

AH Labdi - 2021 - osf.io
Since it was first reported in late 2019, SARS-Cov-2 had a global impact on human physical
and mental health, as well as on their social life and economic endeavor. In one year, the …

[HTML][HTML] Repurposing of known drugs for COVID-19 using molecular docking and simulation analysis

P Bhanu, AS Setlur, K Chandrashekar, V Niranjan… - …, 2023 - ncbi.nlm.nih.gov
We selected fifty one drugs already known for their potential disease treatment roles in
various studies and subjected to docking and molecular docking simulation (MDS) analyses …

Facile detection of peptide-protein interactions using an electrophoretic crosslinking shift assay

B Parker, E Weiss - bioRxiv, 2024 - biorxiv.org
Protein-protein interactions with high specificity and low affinity are functionally important but
are not comprehensively understood because they are difficult to identify. Particularly …

Evolution of targets at the host-pathogen interface

C Beaudoin - 2024 - repository.cam.ac.uk
Using comparative genomics, I investigate the protein-coding potential of globally-
distributed Mtb strains. Previous reports had suggested that the pan-genome (or all unique …