miRNAs insights into rheumatoid arthritis: Favorable and detrimental aspects of key performers

AS Doghish, A Ismail, HA El-Mahdy, SY Elkhawaga… - Life Sciences, 2023 - Elsevier
Rheumatoid arthritis (RA) is a severe autoimmune inflammation that mostly affects the joints.
It's a multifactorial disease. Its clinical picture depends on genetic and epigenetic factors …

miRNAs; a novel strategy for the treatment of COVID‐19

H Ying, M Ebrahimi, M Keivan… - Cell biology …, 2021 - Wiley Online Library
Abstract Coronavirus disease 2019 (COVID‐19) is the seventh member of the bat severe
acute respiratory syndrome family. COVID‐19 can fuse their envelopes with the host cell …

[HTML][HTML] Epigenetic regulator miRNA pattern differences among SARS-CoV, SARS-CoV-2, and SARS-CoV-2 world-wide isolates delineated the mystery behind the …

MAAK Khan, MRU Sany, MS Islam… - Frontiers in genetics, 2020 - frontiersin.org
A detailed understanding of the molecular mechanism of SARS-CoV-2 pathogenesis is still
elusive, and there is a need to address its deadly nature and to design effective …

[HTML][HTML] Computational analysis of microRNA-mediated interactions in SARS-CoV-2 infection

MDS Demirci, A Adan - PeerJ, 2020 - peerj.com
MicroRNAs (miRNAs) are post-transcriptional regulators of gene expression found in more
than 200 diverse organisms. Although it is still not fully established if RNA viruses could …

DIANA-microT 2023: including predicted targets of virally encoded miRNAs

S Tastsoglou, A Alexiou, D Karagkouni… - Nucleic acids …, 2023 - academic.oup.com
DIANA-microT-CDS is a state-of-the-art miRNA target prediction algorithm catering the
scientific community since 2009. It is one of the first algorithms to predict miRNA binding …

SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes

P Pawlica, TA Yario, S White, J Wang… - Proceedings of the …, 2021 - National Acad Sciences
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of
coronavirus disease (COVID-19), continues to be a pressing health concern. In this study …

[HTML][HTML] MicroRNA mimics or inhibitors as antiviral therapeutic approaches against COVID-19

C Hum, J Loiselle, N Ahmed, TA Shaw, C Toudic… - Drugs, 2021 - Springer
Coronaviruses, such as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
responsible for the coronavirus disease 2019 (COVID-19) pandemic, present a significant …

The emerging role of microRNAs in the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection

R Mirzaei, F Mahdavi, F Badrzadeh… - International …, 2021 - Elsevier
The novel coronavirus disease 2019 (COVID-19) pandemic has imposed significant public
health problems for the human populations worldwide after the 1918 influenza A virus …

A virus‐derived microRNA targets immune response genes during SARS‐CoV‐2 infection

M Singh, M Chazal, P Quarato, L Bourdon… - EMBO …, 2022 - embopress.org
SARS‐CoV‐2 infection results in impaired interferon response in patients with severe
COVID‐19. However, how SARS‐CoV‐2 interferes with host immune responses is …

[HTML][HTML] SARS-CoV-2 RNA elements share human sequence identity and upregulate hyaluronan via NamiRNA-enhancer network

W Li, S Yang, P Xu, D Zhang, Y Tong, L Chen, B Jia… - …, 2022 - thelancet.com
Summary Background Since late 2019, SARS-CoV-2 infection has resulted in COVID-19
accompanied by diverse clinical manifestations. However, the underlying mechanism of how …