Revisiting the stress concept: implications for affective disorders
BS McEwen, H Akil - Journal of Neuroscience, 2020 - Soc Neuroscience
Over the last 50 years, the concept of stress has evolved significantly, and our
understanding of the underlying neurobiology has expanded dramatically. Rather than …
understanding of the underlying neurobiology has expanded dramatically. Rather than …
POMC: the physiological power of hormone processing
E Harno, T Gali Ramamoorthy, AP Coll… - Physiological …, 2018 - journals.physiology.org
Pro-opiomelanocortin (POMC) is the archetypal polypeptide precursor of hormones and
neuropeptides. In this review, we examine the variability in the individual peptides produced …
neuropeptides. In this review, we examine the variability in the individual peptides produced …
Nucleotide sequence of cloned cDNA for bovine corticotropin-β-lipotropin precursor
S Nakanishi, A Inoue, T Kita, A Inoue, M Nakamura… - Nature, 1979 - nature.com
The nucleotide sequence of a 1,091-base pair cloned cDNA insert encoding bovine
corticotropin-β-lipotropin precursor mRNA is reported. The corresponding amino acid …
corticotropin-β-lipotropin precursor mRNA is reported. The corresponding amino acid …
Targeting melanocortin receptors as a novel strategy to control inflammation
Adrenocorticotropic hormone and α-, β-, and γ-melanocyte-stimulating hormones,
collectively called melanocortin peptides, exert multiple effects upon the host. These effects …
collectively called melanocortin peptides, exert multiple effects upon the host. These effects …
Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues
AI Smith, JW Funder - Endocrine reviews, 1988 - academic.oup.com
Introduction More than 20 yr ago, in an elegant series of pulsechase studies, Steiner and
Oyer (1) demonstrated that insulin is synthesized in pancreatic islet cells as part of a larger …
Oyer (1) demonstrated that insulin is synthesized in pancreatic islet cells as part of a larger …
Structure of a yeast pheromone gene (MFα): a putative α-factor precursor contains four tandem copies of mature α-factor
J Kurjan, I Herskowitz - Cell, 1982 - cell.com
We have cloned and sequenced a gene (M&x) coding for a-factor, a tridecapeptide mating
factor secreted by yeast a! cells. A plasmid carrying the MFcw gene was identified by …
factor secreted by yeast a! cells. A plasmid carrying the MFcw gene was identified by …
[HTML][HTML] Melanocortin regulation of inflammation
W Wang, DY Guo, YJ Lin, YX Tao - Frontiers in endocrinology, 2019 - frontiersin.org
Adrenocorticotropic hormone (ACTH), and α-, β-, and γ-melanocyte-stimulating hormones (α-
, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin …
, β-, γ-MSH), collectively known as melanocortins, together with their receptors (melanocortin …
The role of endorphins in stress: Evidence and speculations
S Amir, ZW Brown, Z Amit - Neuroscience & Biobehavioral Reviews, 1980 - Elsevier
Several lines of evidence suggest that the endogenous opioid peptides endorphins may
play a role in the defensive response of the organism to stress. The present paper …
play a role in the defensive response of the organism to stress. The present paper …
Primary structure of the human Met-and Leu-enkephalin precursor and its mRNA
The nucleotide sequence of a complete cDNA copy of enkephalin precursor mRNA from
human phaeochromocytoma is reported. The corresponding amino acid sequence shows …
human phaeochromocytoma is reported. The corresponding amino acid sequence shows …
Increases in plasma beta-endorphin/beta-lipotropin immunoreactivity after treadmill running in humans
PA Farrell, WK Gates, MG Maksud… - Journal of Applied …, 1982 - journals.physiology.org
Six well-trained endurance athletes were studied to determine if submaximal treadmill
exercise results in increased plasma levels of beta-endorphin/beta-lipotropin (Bh-Ep/Bh …
exercise results in increased plasma levels of beta-endorphin/beta-lipotropin (Bh-Ep/Bh …