Sepsis is a potentially life-threatening condition caused by a systemic dysregulated host
response to infection. The brain is particularly susceptible to the effects of sepsis with clinical …

Orexins [orexin-A (OXA) and orexin-B (OXB)] are two isoforms of neuropeptides produced by
the hypothalamus. The main biological actions of orexins, focused on the central nervous …

Background Neuroinflammation often results in enduring cognitive impairment and is a risk
factor for postoperative cognitive dysfunction. There are currently no effective treatments for …

Background Considerable evidence has shown that neuroinflammation and oxidative stress
play an important role in the pathophysiology of postoperative cognitive dysfunction (POCD) …

Abstract miR‑23b is a multifunctional microRNA that contributes to the regulation of multiple
signaling pathways. It has been reported that miR‑23b prevents multiple autoimmune …

Sepsis is one of the highest causes of mortality in hospitalized people and a common
complication in both surgical and clinical patients admitted to hospital for non-infectious …

迷走神经刺激对脓毒症相关性脑病大鼠的保护作用 Page 1 · 509 · 中华危重病急救医学2015 年6
月第27 卷第6 期Chin Crit Care Med,June 2015,Vol.27,No.6 · 论著· 迷走神经刺激对脓毒症相关 …

Результаты международных исследований указывают на ежегодный рост частоты и
актуальности сепсиса в реанимационных отделениях. Одним из наиболее ранних …

Abstract Phoenixin-14 (PNX-14) has a wide bioactivity in the central nervous system. Its role
in the hypothalamus has been investigated, and it has been reported that it is involved in the …

Delirium, or acute confusional state, is a common manifestation in diseases that originate
outside the central nervous system, affecting 30–40% of elderly hospitalized patients and up …