Background: Anhepatic animal models are suitable for simulating acute liver failure.
Hepatectomy in pigs includes en bloc resection of the vena cava, and therefore, a temporary …

Introduction Several anhepatic pig models were developed in the past. Most models suffer
from short anhepatic survival times due to insufficient postoperative intensive care unit (ICU) …

Total hepatectomy in animals provides an irreversible model of acute liver failure. Vascular
reconstruction in this model of acute liver failure was modified and characterized for the use …

Long-term maintenance of hepatocyte viability and differentiated function expression is
crucial for bioartificial liver support. The maintenance of hepatocyte function in a bioreactor …

Purpose. A standard protocol of ischemic liver failure in pigs was examined to establish a
system for assessing the efficacy of a bioartificial liver, based on clinical practice. Methods …

Acute liver failure (ALF) is a rare but devastating clinical syndrome with multiple causes and
a variable course. The mortality rate is high. Orthotopic liver transplantation is the only …

Acutee liver failure is a complex and devastating consequence of acute liver injury.. It is
characterized by hepatic encephalopathy, jaundice, coagulopathy and high mortalityy rates …