[HTML][HTML] Bigels as drug delivery systems: From their components to their applications

A Martín-Illana, F Notario-Pérez, R Cazorla-Luna… - Drug discovery today, 2022 - Elsevier
Highlights•Bigels are systems that usually result from mixing a hydrogel and an
organogel.•A hydrophilic biopolymer is commonly the structuring agent of the aqueous …

[HTML][HTML] Bigels and multi-component organogels: An overview from rheological perspective

A Shakeel, U Farooq, D Gabriele, AG Marangoni… - Food …, 2021 - Elsevier
Background Polymeric gels, an important class of soft matter systems, are widely used for
commercial applications particularly in food products (ie, saturated fat replacement). The …

Development and characterization of novel bigels based on monoglyceride-beeswax oleogel and high acyl gellan gum hydrogel for lycopene delivery

Q Zhu, J Gao, L Han, K Han, W Wei, T Wu, J Li… - Food Chemistry, 2021 - Elsevier
The aim of present study was to develop novel bigels as a semi-solid vehicle for lycopene
delivery. Bigels were prepared by using the mixture of glycerol monostearate (GMS) …

Bigels as delivery systems: Potential uses and applicability in food

A Francavilla, MG Corradini, IJ Joye - Gels, 2023 - mdpi.com
Bigels have been mainly applied in the pharmaceutical sector for the controlled release of
drugs or therapeutics. However, these systems, with their intricate structures, hold great …

Key characteristics and modelling of bigels systems: A review

A Shakeel, U Farooq, T Iqbal, S Yasin, FR Lupi… - Materials Science and …, 2019 - Elsevier
Bigels are interesting semisolid formulations with better properties for different applications
such as cosmetics and pharmaceutical systems. Due to the mixing of two phases of different …

Bigels as novel carriers of bioactive compounds: Applications and research trends

B Hashemi, E Assadpour, SM Jafari - Food Hydrocolloids, 2024 - Elsevier
Bigels have drawn more attention recently than other carriers because of their improved
storage stability and potential for longer intestinal release. Due to their poor solubility, quick …

Status and future scope of soft nanoparticles-based hydrogel in wound healing

MHM Sari, AF Cobre, R Pontarolo, LM Ferreira - Pharmaceutics, 2023 - mdpi.com
Wounds are alterations in skin integrity resulting from any type of trauma. The healing
process is complex, involving inflammation and reactive oxygen species formation …

Structural Characterization and In Vivo Anti-Inflammatory Activity of Fucoidan from Cystoseira crinita (Desf.) Borry

E Apostolova, P Lukova, A Baldzhieva, C Delattre… - Marine drugs, 2022 - mdpi.com
The aim of this study was to evaluate the effects of fucoidan isolated from C. crinita on
histamine-induced paw inflammation in rats, and on the serum levels of TNF-α, IL-1β, IL-6 …

A transferosome-loaded bigel for enhanced transdermal delivery and antibacterial activity of vancomycin hydrochloride

R Maji, CA Omolo, Y Jaglal, S Singh… - International Journal of …, 2021 - Elsevier
Transdermal drug delivery is an attractive route of administration relative to other routes as it
offers enhanced therapeutic efficacy. However, due to poor skin permeability of certain …

Polymeric gels and their application in the treatment of psoriasis vulgaris: A review

A Kulawik-Pióro, M Miastkowska - International Journal of Molecular …, 2021 - mdpi.com
Psoriasis is a chronic skin disease, and it is especially characterized by the occurrence of
red, itchy, and scaly eruptions on the skin. The quality of life of patients with psoriasis is …