[HTML][HTML] COVID-19 vaccine update: vaccine effectiveness, SARS-CoV-2 variants, boosters, adverse effects, and immune correlates of protection
Abstract Coronavirus Disease 2019 (COVID-19) has been the most severe public health
challenge in this century. Two years after its emergence, the rapid development and …
challenge in this century. Two years after its emergence, the rapid development and …
Modern subunit vaccines: development, components, and research opportunities
Traditional vaccines, based on the administration of killed or attenuated microorganisms,
have proven to be among the most effective methods for disease prevention. Safety issues …
have proven to be among the most effective methods for disease prevention. Safety issues …
[HTML][HTML] Designing a novel multi-epitope vaccine to evoke a robust immune response against pathogenic multidrug-resistant Enterococcus faecium bacterium
Enterococcus faecium is an emerging ESKAPE bacterium that is capable of causing severe
public health complications in humans. There are currently no licensed treatments or …
public health complications in humans. There are currently no licensed treatments or …
Structure-based design of a fusion glycoprotein vaccine for respiratory syncytial virus
JS McLellan, M Chen, MG Joyce, M Sastry… - science, 2013 - science.org
Respiratory syncytial virus (RSV) is the leading cause of hospitalization for children under 5
years of age. We sought to engineer a viral antigen that provides greater protection than …
years of age. We sought to engineer a viral antigen that provides greater protection than …
Integrating animal temperament within ecology and evolution
Temperament describes the idea that individual behavioural differences are repeatable over
time and across situations. This common phenomenon covers numerous traits, such as …
time and across situations. This common phenomenon covers numerous traits, such as …
Vaccines, new opportunities for a new society
R Rappuoli, M Pizza, G Del Giudice… - Proceedings of the …, 2014 - National Acad Sciences
Vaccination is the most effective medical intervention ever introduced and, together with
clean water and sanitation, it has eliminated a large part of the infectious diseases that once …
clean water and sanitation, it has eliminated a large part of the infectious diseases that once …
[HTML][HTML] Recombinant vaccines and the development of new vaccine strategies
IP Nascimento, LCC Leite - Brazilian journal of medical and biological …, 2012 - SciELO Brasil
Vaccines were initially developed on an empirical basis, relying mostly on attenuation or
inactivation of pathogens. Advances in immunology, molecular biology, biochemistry …
inactivation of pathogens. Advances in immunology, molecular biology, biochemistry …
Broadly neutralizing antiviral antibodies
D Corti, A Lanzavecchia - Annual review of immunology, 2013 - annualreviews.org
A fascinating aspect of viral evolution relates to the ability of viruses to escape the adaptive
immune response. The widely held view has been that the great variability of viral …
immune response. The widely held view has been that the great variability of viral …
[HTML][HTML] B-cell–lineage immunogen design in vaccine development with HIV-1 as a case study
Failure of immunization with the HIV-1 envelope to induce broadly neutralizing antibodies
against conserved epitopes is a major barrier to producing a preventive HIV-1 vaccine …
against conserved epitopes is a major barrier to producing a preventive HIV-1 vaccine …
Designing multi-epitope vaccine against Staphylococcus aureus by employing subtractive proteomics, reverse vaccinology and immuno-informatics approaches
Staphylococcus aureus is a deadly human bacterial pathogen that causes a wide variety of
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …
clinical manifestations. Invasive S. aureus infections in hospitals and the community are one …