High-resolution magic angle spinning NMR spectroscopy: Application to biomedical studies -
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Cataracts are one of the most prevalent diseases of the lens, affecting its transparency and
are the leading cause of reversible blindness in the world. The clarity of the lens is essential …

Purpose Vitreoretinal disorders lack specific biomarkers that define either disease type or
response to treatment. We have used NMR-based metabolomic analysis of human vitreous …

High‐resolution magic angle spinning (HRMAS) MRS allows for direct measurements of non‐
liquid tissue and cell specimens to present valuable insights into the cellular metabolisms of …

Metabolomics, the analysis of the metabolite profile in body fluids or tissues, is being applied
to the analysis of a number of different diseases as well as being used in following …

The transparent anterior segment of the human eye (cornea and lens), as well as neural
retina, are the principal target of UV radiation for both acute and long-term exposure. The …

Ionizing radiation may cause cardiotoxicity not only at high, but even at low (considered as
harmless) doses, yet the molecular mechanisms of the heart's response to low doses are not …

High-resolution magic angle spinning (HRMAS) is the combined application of high-
resolution NMR experiments with dipolar-and susceptibility-reducing sample rotation to …

Blue light exposure induced retinal damage has been extensively studied. Retinal damages
are closely associated with cellular and biochemical changes occurring in the vitreous and …

Metabonomics is a new technology providing broad information about dynamic metabolic
responses in living systems to pathophysiological stimuli or genetic modification. Nuclear …