Sleep-wake disturbances after traumatic brain injury: synthesis of human and animal studies
Sleep–wake disturbances following traumatic brain injury (TBI) are increasingly recognized
as a serious consequence following injury and as a barrier to recovery. Injury-induced sleep …
as a serious consequence following injury and as a barrier to recovery. Injury-induced sleep …
The bidirectional relationship between sleep and inflammation links traumatic brain injury and Alzheimer's disease
TRF Green, JB Ortiz, S Wonnacott… - Frontiers in …, 2020 - frontiersin.org
Traumatic brain injury (TBI) and Alzheimer's disease (AD) are diseases during which the fine-
tuned autoregulation of the brain is lost. Despite the stark contrast in their causal …
tuned autoregulation of the brain is lost. Despite the stark contrast in their causal …
Rod microglia: a morphological definition
SE Taylor, C Morganti-Kossmann, J Lifshitz, JM Ziebell - PloS one, 2014 - journals.plos.org
Brain microglial morphology relates to function, with ramified microglia surveying the micro-
environment and amoeboid microglia engulfing debris. One subgroup of microglia, rod …
environment and amoeboid microglia engulfing debris. One subgroup of microglia, rod …
Resolvins AT-D1 and E1 differentially impact functional outcome, post-traumatic sleep, and microglial activation following diffuse brain injury in the mouse
JL Harrison, RK Rowe, TW Ellis, NS Yee… - Brain, behavior, and …, 2015 - Elsevier
Traumatic brain injury (TBI) is induced by mechanical forces which initiate a cascade of
secondary injury processes, including inflammation. Therapies which resolve the …
secondary injury processes, including inflammation. Therapies which resolve the …
Glial immune-related pathways mediate effects of closed head traumatic brain injury on behavior and lethality in Drosophila
B van Alphen, S Stewart, M Iwanaszko, F Xu, K Li… - PLoS …, 2022 - journals.plos.org
In traumatic brain injury (TBI), the initial injury phase is followed by a secondary phase that
contributes to neurodegeneration, yet the mechanisms leading to neuropathology in vivo …
contributes to neurodegeneration, yet the mechanisms leading to neuropathology in vivo …
The effect of traumatic brain injury on sleep architecture and circadian rhythms in mice—a comparison of high-frequency head impact and controlled cortical injury
Simple Summary Traumatic brain injury (TBI) is a significant risk factor for the development
of sleep and circadian rhythm impairments. In order to understand if TBI models with …
of sleep and circadian rhythm impairments. In order to understand if TBI models with …
Clinical relevance of midline fluid percussion brain injury: acute deficits, chronic morbidities and the utility of biomarkers
J Lifshitz, RK Rowe, DR Griffiths, MN Evilsizor… - Brain injury, 2016 - Taylor & Francis
Background: After 30 years of characterisation and implementation, fluid percussion injury
(FPI) is firmly recognised as one of the best-characterised reproducible and clinically …
(FPI) is firmly recognised as one of the best-characterised reproducible and clinically …
Roadmap for advancing pre-clinical science in traumatic brain injury
Pre-clinical models of disease have long played important roles in the advancement of new
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …
treatments. However, in traumatic brain injury (TBI), despite the availability of numerous …
Sleep disruption exacerbates and prolongs the inflammatory response to traumatic brain injury
ZM Tapp, JE Kumar, KG Witcher, RR Atluri… - Journal of …, 2020 - liebertpub.com
Traumatic brain injury (TBI) alters stress responses, which may influence neuroinflammation
and behavioral outcome. Sleep disruption (SD) is an understudied post-injury environmental …
and behavioral outcome. Sleep disruption (SD) is an understudied post-injury environmental …
Many faces of sleep regulation: beyond the time of day and prior wake time
The two‐process model of sleep regulation posits two main processes regulating sleep: the
circadian process controlled by the circadian clock and the homeostatic process that …
circadian process controlled by the circadian clock and the homeostatic process that …