Inhaled nitric oxide for acute respiratory distress syndrome (ARDS) in children and adults

F Gebistorf, O Karam, J Wetterslev… - Cochrane database of …, 2016 - cochranelibrary.com
Background Acute hypoxaemic respiratory failure (AHRF) and mostly acute respiratory
distress syndrome (ARDS) are critical conditions. AHRF results from several systemic …

Hypoxic pulmonary vasoconstriction

JT Sylvester, LA Shimoda, PI Aaronson… - Physiological …, 2012 - journals.physiology.org
It has been known for more than 60 years, and suspected for over 100, that alveolar hypoxia
causes pulmonary vasoconstriction by means of mechanisms local to the lung. For the last …

Inhaled nitric oxide versus conventional therapy: effect on oxygenation in ARDS

JR Michael, RG Barton, JR Saffle, M Mone… - American journal of …, 1998 - atsjournals.org
A randomized, controlled clinical trial was performed with patients with acute respiratory
distress syndrome (ARDS) to compare the effect of conventional therapy or inhaled nitric …

The acute respiratory distress syndrome: Definitions, severity and clinical outcome An analysis of 101 clinical investigations

P Krafft, P Fridrich, T Pernerstorfer, RD Fitzgerald… - Intensive care …, 1996 - Springer
Objective To determine possible changes in outcome from acute respiratory distress
syndrome (ARDS) and to compare severity of lung injury and methods of treatment from …

Dose–response characteristics during long-term inhalation of nitric oxide in patients with severe acute respiratory distress syndrome: a prospective, randomized …

H Gerlach, D Keh, A Semmerow, T Busch… - American journal of …, 2003 - atsjournals.org
Inhaled nitric oxide (NO) improves systemic oxygenation (PaO2/FIO2) in adult patients with
acute respiratory distress syndrome (ARDS). However, individual response varies, and …

Nasal nitric oxide in man

JON Lundberg, E Weitzberg - Thorax, 1999 - thorax.bmj.com
The past decade has witnessed an explosion in the interest of biologists in the gas nitric
oxide (NO). This highly reactive free radical, first considered only a noxious air pollutant, is …

Nitric oxide and the paranasal sinuses

JO Lundberg - The Anatomical Record: Advances in Integrative …, 2008 - Wiley Online Library
The discovery within the paranasal sinuses for the production of nitric oxide (NO) has altered
the traditional explanations of sinus physiology. This review article reports the ongoing …

Nitric oxide, the biological mediator of the decade: fact or fiction?

S Singh, TW Evans - European Respiratory Journal, 1997 - Eur Respiratory Soc
Nitric oxide (NO), an atmospheric gas and free radical, is also an important biological
mediator in animals and humans. Its enzymatic synthesis by constitutive (c) and inducible (i) …

Inhibition of platelet aggregation by inhaled nitric oxide in patients with acute respiratory distress syndrome

CM Samama, M Diaby, JL Fellahi… - The Journal of the …, 1995 - pubs.asahq.org
Background Nitric oxide inhibits platelet adhesion and aggregation in vitro. The aim of this
prospective study was to assess the platelet antiaggregating activity of nitric oxide …

The clinical implications of isolated alpha1 adrenergic stimulation

RH Thiele, EC Nemergut, C Lynch III - Anesthesia & Analgesia, 2011 - journals.lww.com
Phenylephrine is a direct-acting, predominantly α1 adrenergic receptor agonist used by
anesthesiologists and intensivists to treat hypotension. A variety of physiologic studies …