Emerging risk biomarkers in cardiovascular diseases and disorders

RK Upadhyay - Journal of lipids, 2015 - Wiley Online Library
Present review article highlights various cardiovascular risk prediction biomarkers by
incorporating both traditional risk factors to be used as diagnostic markers and recent …

Effects of P2Y12 receptor antagonists beyond platelet inhibition – comparison of ticagrelor with thienopyridines

S Nylander, R Schulz - British journal of pharmacology, 2016 - Wiley Online Library
The effect and clinical benefit of P2Y12 receptor antagonists may not be limited to platelet
inhibition and the prevention of arterial thrombus formation. Potential additional effects …

Antioxidant Properties of oral antithrombotic therapies in atherosclerotic Disease and Atrial Fibrillation

L Falco, V Tessitore, G Ciccarelli, M Malvezzi… - Antioxidants, 2023 - mdpi.com
The thrombosis-related diseases are one of the leading causes of illness and death in the
general population, and despite significant improvements in long-term survival due to …

Circulating and Urinary Concentrations of Malondialdehyde in Aging Humans in Health and Disease: Review and Discussion

D Tsikas, SA Tsikas, M Mikuteit, S Ückert - Biomedicines, 2023 - mdpi.com
(1) Background: Malondialdehyde (MDA) is a major and stable product of oxidative stress.
MDA circulates in the blood and is excreted in the urine in its free and conjugated forms …

Antiplatelet and myocardial protective effect of Shexiang Tongxin Dropping Pill in patients undergoing percutaneous coronary intervention: A randomized controlled …

Y Lin, K Jiao, B Liu, L Fang, S Meng - Journal of Integrative Medicine, 2022 - Elsevier
Background High on-clopidogrel platelet reactivity could be partially explained by loss-of-
function alleles of CYP2C19, the enzyme that converts clopidogrel into its active form …

Clopidogrel combats neuroinflammation and enhances learning behavior and memory in a rat model of Alzheimer's disease

NEA Khalaf, FM El Banna, MY Youssef… - Pharmacology …, 2020 - Elsevier
Background and aim Alzheimer's disease (AD) is a progressive neurodegenerative disease.
Multiple molecular mechanisms have been employed in its pathogenesis such as Amyloid β …

Purinergic signaling in atherosclerosis

D Ferrari, L Vitiello, M Idzko, A la Sala - Trends in molecular medicine, 2015 - cell.com
Cell surface expression of specific receptors and ecto-nucleotidases makes extracellular
nucleotides such as ATP, ADP, UTP, and adenosine suitable as signaling molecules for …

Serum anti-AP3D1 antibodies are risk factors for acute ischemic stroke related with atherosclerosis

SY Li, Y Yoshida, E Kobayashi, M Kubota… - Scientific reports, 2021 - nature.com
Atherosclerosis has been considered as the main cause of morbidity, mortality, and disability
worldwide. The first screening for antigen markers was conducted using the serological …

Antiplatelet effects of clopidogrel and aspirin after interventional patent foramen ovale/atrium septum defect closure

A Polzin, L Dannenberg, V Sophia Popp, M Kelm… - Platelets, 2016 - Taylor & Francis
The optimal antiplatelet therapy after patent foramen ovale (PFO)/atrium septum defect
(ASD) closure is a matter of discussion. It is challenging as inter-individual responses to …

Clopidogrel Protects Endothelium by Hindering TNFα‐Induced VCAM‐1 Expression through CaMKKβ/AMPK/Nrf2 Pathway

H Yang, P Zhao, S Tian - Journal of diabetes research, 2016 - Wiley Online Library
Clopidogrel (INN), an oral antiplatelet drug, has been revealed to have a number of
biological properties, for instance, anti‐inflammation and antioxidation. Oxidative stress …