The gut microbiota is a complex system, consisting of a dynamic population of
microorganisms, involved in the regulation of the host's homeostasis. A vast number of …

Pregnancy induces a number of immunological, hormonal, and metabolic changes that are
necessary for the mother to adapt her body to this new physiological situation. The …

Objective Obesity-induced by high-fat diet (HFD) is associated with liver steatosis, oxidative
stress and mitochondrial dysfunction, which can be eluded by the co-administration of the …

Strong evidence suggests that early-life exposures to suboptimal environmental factors,
including those in utero, influence our long-term metabolic health. This has been termed …

There is extensive evidence supporting the interplay between metabolism and immune
response, that have evolved in close relationship, sharing regulatory molecules and …

Non-alcoholic fatty liver disease (NAFLD) is a major health issue worldwide, being
frequently associated with obesity, unbalanced dietary regimens, and reduced physical …

Hypertension can originate in early life caused by perinatal high-fat (HF) consumption. Gut
microbiota and their metabolites short chain fatty acids (SCFAs), trimethylamine (TMA), and …

Obesity and elevated serum lipids are associated with a threefold increase in the risk of
developing atherosclerosis, a condition that underlies stroke, myocardial infarction, and …

Gestational diabetes mellitus (GDM), one of the most common endocrine pathologies during
pregnancy, is defined as any degree of glucose intolerance with onset or first discovery in …

Key points Maternal obesity has been associated with shifts in intestinal microbiota, which
may contribute to impaired barrier function Impaired barrier function may expose the …