Transition metal-catalysed C–H activation has emerged as an increasingly powerful platform
for molecular syntheses, enabling applications to natural product syntheses, late-stage …

Alkylation reactions represent an important organic transformation to form C–C bonds. In
addition to conventional approaches with alkyl halides or sulfonates as alkylating agents …

Hydroaminoalkylation is a powerful, atom-economic catalytic reaction for the reaction of
amines with alkenes and alkynes. This C–H functionalization reaction allows for the atom …

Metallo-photoredox catalysis has redefined the available bond disconnections in the
synthetic arsenal. By harnessing the one-electron chemistry of photoredox catalysis in …

Pd (II)-catalyzed α-C (sp3)–H arylation of pyrrolidines, piperidines, azepanes, and N-
methylamines with arylboronic acids has been developed for the first time. This …

This short review highlights recent catalyst developments from group 3–5 elements reported
in the past few years to promote two highly atom-saving transformations, namely …

Hydroaminoalkylation is a 100% atom economic method for forming Csp3–Csp3 bonds
through C–H activation α to an amine and subsequent reaction with an alkene. When …

Conspectus Titanium, as the second most abundant transition metal in the earth's crust,
lends itself as a sustainable and inexpensive resource in catalysis. Its nontoxicity and …

The development of new and practical 3‐pentoxythiocarbonyl auxiliaries for IrI‐catalyzed C−
H alkylation of azacycles is described. This method allows for the α‐C− H alkylation of a …

The recent development and progress of early-transition-metal-catalyzed C–H alkylation
adjacent to nitrogen of unprotected amines with alkenes are summarized. Group 4 and 5 …