Chemokines are an indispensable component of our immune system through the regulation
of directional migration and activation of leukocytes. CXCL8 is the most potent human …

Neutrophils are the most abundant leukocytes in the circulation, and have been regarded as
first line of defense in the innate arm of the immune system. They capture and destroy …

The nervous and immune systems are intricately linked. Although psychological stress is
known to modulate immune function, mechanistic pathways linking stress networks in the …

Structured models of ontogenic, phenotypic and functional diversity have been instrumental
for a renewed understanding of the biology of immune cells, such as macrophages and …

Neutrophils are specialized innate cells that require constant replenishment from
proliferative bone marrow (BM) precursors as a result of their short half-life. Although it is …

Neutrophils are indispensable antagonists of microbial infection and facilitators of wound
healing. In the cancer setting, a newfound appreciation for neutrophils has come into view …

For our immune system to contain or eliminate malignant solid tumours, both myeloid and
lymphoid haematopoietic cells must not only extravasate from the bloodstream into the …

Phagocytes form a family of immune cells that play a crucial role in tissue maintenance and
help orchestrate the immune response. This family of cells can be separated by their nuclear …

Traditionally, neutrophils have been acknowledged to be the first immune cells that are
recruited to an inflamed tissue and have mainly been considered in the context of acute …

Closed circulatory systems underlie the function of vertebrate organs, but in long bones their
structure is unclear although they constitute the exit route for bone marrow (BM) leukocytes …