Basic ultrasound head-to-toe skills for intensivists in the general and neuro intensive care unit population: consensus and expert recommendations of the European …

C Robba, A Wong, D Poole, A Al Tayar… - Intensive care …, 2021 - Springer
Purpose To provide consensus, and a list of experts' recommendations regarding the basic
skills for head-to-toe ultrasonography in the intensive care setting. Methods The Executive …

Regulation of the cerebral circulation: bedside assessment and clinical implications

J Donnelly, KP Budohoski, P Smielewski, M Czosnyka - Critical care, 2016 - Springer
Regulation of the cerebral circulation relies on the complex interplay between
cardiovascular, respiratory, and neural physiology. In health, these physiologic systems act …

Targeting autoregulation-guided cerebral perfusion pressure after traumatic brain injury (COGiTATE): a feasibility randomized controlled clinical trial

J Tas, E Beqiri, RC van Kaam, M Czosnyka… - Journal of …, 2021 - liebertpub.com
Managing traumatic brain injury (TBI) patients with a cerebral perfusion pressure (CPP) near
to the cerebral autoregulation (CA)-guided “optimal” CPP (CPPopt) value is associated with …

Tissue perfusion pressure enables continuous hemodynamic evaluation and risk prediction in the intensive care unit

A Chandrasekhar, R Padrós-Valls, R Pallarès-López… - Nature Medicine, 2023 - nature.com
Abstract Treatment of circulatory shock in critically ill patients requires management of blood
pressure using invasive monitoring, but uncertainty remains as to optimal individual blood …

Twenty-five years of intracranial pressure monitoring after severe traumatic brain injury: a retrospective, single-center analysis

J Donnelly, M Czosnyka, H Adams, D Cardim… - …, 2019 - journals.lww.com
BACKGROUND Intracranial pressure (ICP) is a clinically important variable after severe
traumatic brain injury (TBI) and has been monitored, along with clinical outcome, for over 25 …

Feasibility of individualised severe traumatic brain injury management using an automated assessment of optimal cerebral perfusion pressure: the COGiTATE phase II …

E Beqiri, P Smielewski, C Robba, M Czosnyka… - BMJ open, 2019 - bmjopen.bmj.com
Introduction Individualising therapy is an important challenge for intensive care of patients
with severe traumatic brain injury (TBI). Targeting a cerebral perfusion pressure (CPP) …

Individualizing thresholds of cerebral perfusion pressure using estimated limits of autoregulation

J Donnelly, M Czosnyka, H Adams, C Robba… - Critical care …, 2017 - journals.lww.com
Objectives: In severe traumatic brain injury, cerebral perfusion pressure management based
on cerebrovascular pressure reactivity index has the potential to provide a personalized …

Transcranial Doppler: a stethoscope for the brain‐neurocritical care use

C Robba, D Cardim, M Sekhon… - Journal of …, 2018 - Wiley Online Library
Transcranial Doppler (TCD) ultrasonography is a noninvasive bedside monitoring technique
that can evaluate cerebral blood flow hemodynamics in the intracranial arterial vasculature …

Pressure autoregulation measurement techniques in adult traumatic brain injury, part II: a scoping review of continuous methods

FA Zeiler, J Donnelly, L Calviello… - Journal of …, 2017 - liebertpub.com
A scoping review of the literature was performed systematically on commonly described
continuous autoregulation measurement techniques in adult traumatic brain injury (TBI) to …

[图书][B] Cerebral autoregulation: control of blood flow in the brain

S Payne - 2016 - Springer
Every part of the human brain must be supplied with a sufficient and continuous supply of
blood in order to maintain healthy function. Cerebral autoregulation, the means by which the …