1/f electrophysiological spectra in resting and drug-induced states can be explained by the dynamics of multiple oscillatory relaxation processes

SD Muthukumaraswamy, DTJ Liley - NeuroImage, 2018 - Elsevier
Neurophysiological recordings are dominated by arhythmical activity whose spectra can be
characterised by power-law functions, and on this basis are often referred to as reflecting …

Automation of anaesthesia: a review on multivariable control

JJ Chang, S Syafiie, R Kamil, TA Lim - Journal of clinical monitoring and …, 2015 - Springer
Anaesthesia is a multivariable problem where a combination of drugs are used to induce
desired hypnotic, analgesia and immobility states. The automation of anaesthesia may …

A pilot study for a prospective, randomized, double-blind trial of the influence of anesthetic depth on long-term outcome

TG Short, K Leslie, D Campbell, MTV Chan… - Anesthesia & …, 2014 - journals.lww.com
BACKGROUND: Deep general anesthesia has been associated with increased mortality in
5 observational studies. The association may be causal or an epiphenomenon due to …

Nitrous oxide paradoxically modulates slow electroencephalogram oscillations: implications for anesthesia monitoring

BL Foster, DTJ Liley - Anesthesia & Analgesia, 2011 - journals.lww.com
BACKGROUND: Nitrous oxide (N 2 O) is one of the oldest analgesics/adjuvant agents still in
use today; however, its effects on the human electroencephalogram (EEG) remain unclear. It …

Neural mass model-based tracking of anesthetic brain states

L Kuhlmann, DR Freestone, JH Manton, B Heyse… - NeuroImage, 2016 - Elsevier
Neural mass model-based tracking of brain states from electroencephalographic signals
holds the promise of simultaneously tracking brain states while inferring underlying …

[PDF][PDF] Propofol and remifentanil differentially modulate frontal electroencephalographic activity

DTJ Liley, NC Sinclair, T Lipping, B Heyse… - …, 2010 - academia.edu
Background: The purpose of this study was to evaluate a new, physiologically inspired
method for the analysis of the electroencephalogram during propofol–remifentanil …

Comparisons of electroencephalographically derived measures of hypnosis and antinociception in response to standardized stimuli during target-controlled propofol …

M Shoushtarian, MM Sahinovic… - Anesthesia & …, 2016 - journals.lww.com
BACKGROUND: Current electroencephalogram (EEG)-derived measures provide
information on cortical activity and hypnosis but are less accurate regarding subcortical …

[HTML][HTML] Evidence that alpha blocking is due to increases in system-level oscillatory damping not neuronal population desynchronisation

DTJ Liley, SD Muthukumaraswamy - NeuroImage, 2020 - Elsevier
The attenuation of the alpha rhythm following eyes-opening (alpha blocking) is among the
most robust features of the human electroencephalogram with the prevailing view being that …

Evaluation of the brain anaesthesia response monitor during anaesthesia for cardiac surgery: a double-blind, randomised controlled trial using two doses of fentanyl

M Shoushtarian, DP McGlade, LJ Delacretaz… - Journal of clinical …, 2016 - Springer
The brain anaesthesia response (BAR) monitor uses a method of EEG analysis, based on a
model of brain electrical activity, to monitor the cerebral response to anaesthetic and …

Tracking electroencephalographic changes using distributions of linear models: application to propofol-based depth of anesthesia monitoring

L Kuhlmann, JH Manton, B Heyse… - IEEE Transactions …, 2016 - ieeexplore.ieee.org
Objective: Tracking brain states with electrophysiological measurements often relies on
short-term averages of extracted features and this may not adequately capture the variability …