Management of neonates born at≥ 35 0/7 weeks' gestation with suspected or proven early-onset bacterial sepsis

KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
The incidence of neonatal early-onset sepsis (EOS) has declined substantially over the last
2 decades, primarily because of the implementation of evidence-based intrapartum …

Management of neonates born at≤ 34 6/7 weeks' gestation with suspected or proven early-onset bacterial sepsis

KM Puopolo, WE Benitz, TE Zaoutis, J Cummings… - …, 2018 - publications.aap.org
Early-onset sepsis (EOS) remains a serious and often fatal illness among infants born
preterm, particularly among newborn infants of the lowest gestational age. Currently, most …

Diagnostics for neonatal sepsis: current approaches and future directions

PY Iroh Tam, CM Bendel - Pediatric research, 2017 - nature.com
Progress has been made in the reduction of morbidity and mortality from neonatal sepsis.
However, diagnosis continues to rely primarily on conventional microbiologic techniques …

Reliability of interleukin-6 alone and in combination for diagnosis of early onset neonatal sepsis: Systematic review

J Eichberger, B Resch - Frontiers in Pediatrics, 2022 - frontiersin.org
Neonatal sepsis is a major cause of morbidity and mortality in both preterm and term infants.
Early-onset neonatal sepsis (EONS) presents within the first 72 h of life. Diagnosis is difficult …

Interleukin-6 for early diagnosis of neonatal sepsis with premature rupture of the membranes: A meta-analysis

X Qiu, L Zhang, Y Tong, Y Qu, H Wang, D Mu - Medicine, 2018 - journals.lww.com
Background: Premature rupture of the membranes (PROM) is the principal risk factor for
neonatal sepsis. Interleukin-6 (IL-6) has been investigated for early diagnosis of neonatal …

[HTML][HTML] The fetal inflammatory response syndrome: the origins of a concept, pathophysiology, diagnosis, and obstetrical implications

E Jung, R Romero, L Yeo, R Diaz-Primera… - Seminars in Fetal and …, 2020 - Elsevier
The fetus can deploy a local or systemic inflammatory response when exposed to
microorganisms or, alternatively, to non-infection-related stimuli (eg, danger signals or …

A dormant microbial component in the development of preeclampsia

DB Kell, LC Kenny - Frontiers in medicine, 2016 - frontiersin.org
Preeclampsia (PE) is a complex, multisystem disorder that remains a leading cause of
morbidity and mortality in pregnancy. Four main classes of dysregulation accompany PE …

[HTML][HTML] Clinical chorioamnionitis at term VI: acute chorioamnionitis and funisitis according to the presence or absence of microorganisms and inflammation in the …

R Romero, P Chaemsaithong, N Docheva… - Journal of perinatal …, 2016 - degruyter.com
Objective: Neonates born to mothers with clinical chorioamnionitis at term are at an
increased risk of infection. Acute subchorionitis, chorioamnionitis, and funisitis are …

[HTML][HTML] Platelet to lymphocyte ratio in neonates: a predictor of early onset neonatal sepsis

BC Arcagok, B Karabulut - Mediterranean journal of hematology …, 2019 - ncbi.nlm.nih.gov
Background Neonatal sepsis (NS) is a common systemic disease that causes morbidity and
mortality in newborns. But there is no ideal biomarker that can be used in the early diagnosis …

Cord blood acute phase reactants predict early onset neonatal sepsis in preterm infants

LB Mithal, HL Palac, R Yogev, LM Ernst, KK Mestan - PLOS one, 2017 - journals.plos.org
Background Early onset sepsis (EOS) is a major cause of morbidity and mortality in preterm
infants, yet diagnosis remains inadequate resulting in missed cases or prolonged empiric …