This article summarizes anatomical, neurophysiological, pharmacological, and brain
imaging studies in humans and animals that have provided insights into the neural circuitry …

Most of us live blissfully unaware of the orchestrated function that our internal organs
conduct. When this peace is interrupted, it is often by routine sensations of hunger and urge …

The urothelium, which lines the inner surface of the renal pelvis, the ureters, and the urinary
bladder, not only forms a high-resistance barrier to ion, solute and water flux, and …

Capsaicin is the active ingredient of chili peppers and gives them the characteristic pungent
flavor. Understanding the actions of capsaicin led to the discovery of its receptor, transient …

The urothelium, which lines the renal pelvis, ureters, urinary bladder, and proximal urethra,
forms a high-resistance but adaptable barrier that surveils its mechanochemical …

The afferent innervation of the urinary bladder consists primarily of small myelinated (Aδ)
and unmyelinated (C-fiber) axons that respond to chemical and mechanical stimuli …

Functions of the lower urinary tract to store and periodically eliminate urine are regulated by
a complex neural control system in the brain, spinal cord, and peripheral autonomic ganglia …

Acidosis is a noxious condition associated with inflammation, ischaemia or defective acid
containment. As a consequence, acid sensing has evolved as an important property of …

The bladder is innervated by extrinsic afferents that project into the dorsal horn of the spinal
cord, providing sensory input to the micturition centers within the central nervous system …

OBJECTIVES: To investigate the distribution of the transient receptor potential (TRP) A1 ion
channel in the rat urinary bladder, and to study the effects of hydrogen sulfide (H2S) and …