Considerations for the use of phage therapy in clinical practice

GA Suh, TP Lodise, PD Tamma… - Antimicrobial agents …, 2022 - Am Soc Microbiol
Increasing antimicrobial resistance and medical device-related infections have led to a
renewed interest in phage therapy as an alternative or adjunct to conventional …

Phage therapy for antibiotic-resistant bacterial infections

GF Hatfull, RM Dedrick… - Annual review of medicine, 2022 - annualreviews.org
Antibiotic resistance in bacterial pathogens presents a substantial threat to the control of
infectious diseases. Development of new classes of antibiotics has slowed in recent years …

Antimicrobial photodynamic therapy: Latest developments with a focus on combinatory strategies

R Youf, M Müller, A Balasini, F Thétiot, M Müller… - Pharmaceutics, 2021 - mdpi.com
Antimicrobial photodynamic therapy (aPDT) has become a fundamental tool in modern
therapeutics, notably due to the expanding versatility of photosensitizers (PSs) and the …

Immunogenicity of bacteriophages

K Champagne-Jorgensen, T Luong, T Darby… - Trends in …, 2023 - cell.com
Hundreds of trillions of diverse bacteriophages (phages) peacefully thrive within and on the
human body. However, whether and how phages influence their mammalian hosts is poorly …

Translating phage therapy into the clinic: recent accomplishments but continuing challenges

A Petrovic Fabijan, J Iredell, K Danis-Wlodarczyk… - Plos …, 2023 - journals.plos.org
Phage therapy is a medical form of biological control of bacterial infections, one that uses
naturally occurring viruses, called bacteriophages or phages, as antibacterial agents …

Surgical antibiotic prophylaxis in an era of antibiotic resistance: common resistant bacteria and wider considerations for practice

BD Menz, E Charani, DL Gordon… - Infection and Drug …, 2021 - Taylor & Francis
The increasing incidence of antimicrobial resistance (AMR) presents a global crisis to
healthcare, with longstanding antimicrobial agents becoming less effective at treating and …

Encapsulation and delivery of therapeutic phages

B Loh, VS Gondil, P Manohar, FM Khan… - Applied and …, 2021 - Am Soc Microbiol
Delivery of therapeutic compounds to the site of action is crucial. While many chemical
substances such as beta-lactam antibiotics can reach therapeutic levels in most parts …

Phage therapy: towards a successful clinical trial

A Górski, J Borysowski, R Międzybrodzki - Antibiotics, 2020 - mdpi.com
While phage therapy carried out as compassionate use (experimental therapy) has recently
flourished, providing numerous case reports of supposedly healed patients, clinical trials …

[HTML][HTML] Bacteriophage therapy for staphylococcus aureus infections: a review of animal models, treatments, and clinical trials

L Plumet, N Ahmad-Mansour… - Frontiers in Cellular …, 2022 - frontiersin.org
Staphylococcus aureus (S. aureus) is a common and virulent human pathogen causing
several serious illnesses including skin abscesses, wound infections, endocarditis …

An explorative review on advanced approaches to overcome bacterial resistance by curbing bacterial biofilm formation

F Mohamad, RR Alzahrani, A Alsaadi… - Infection and Drug …, 2023 - Taylor & Francis
The continuous emergence of multidrug-resistant pathogens evoked the development of
innovative approaches targeting virulence factors unique to their pathogenic cascade …