[HTML][HTML] Low back pain in older adults: risk factors, management options and future directions
AYL Wong, J Karppinen, D Samartzis - Scoliosis and spinal disorders, 2017 - Springer
Low back pain (LBP) is one of the major disabling health conditions among older adults
aged 60 years or older. While most causes of LBP among older adults are non-specific and …
aged 60 years or older. While most causes of LBP among older adults are non-specific and …
Emerging therapeutic targets in chordomas: a review of the literature in the genomic era
CM Gill, M Fowkes, RK Shrivastava - Neurosurgery, 2020 - journals.lww.com
Chordomas are rare primary malignant tumors of the bones that occur along the skull base,
spine, and sacrum. Long-term survival and neurological outcome continue to be challenging …
spine, and sacrum. Long-term survival and neurological outcome continue to be challenging …
[HTML][HTML] The driver landscape of sporadic chordoma
Chordoma is a malignant, often incurable bone tumour showing notochordal differentiation.
Here, we defined the somatic driver landscape of 104 cases of sporadic chordoma. We …
Here, we defined the somatic driver landscape of 104 cases of sporadic chordoma. We …
[HTML][HTML] Advanced chordoma treated by first-line molecular targeted therapies: Outcomes and prognostic factors. A retrospective study of the French Sarcoma Group …
L Lebellec, B Chauffert, JY Blay, A Le Cesne… - European journal of …, 2017 - Elsevier
Background To assess the role of first-line Molecular Targeted Therapies (MTTs) in
Advanced chordoma (AC) patients. Methods Retrospective study of 80 patients treated …
Advanced chordoma (AC) patients. Methods Retrospective study of 80 patients treated …
Development of machine learning algorithms for prediction of 5-year spinal chordoma survival
AV Karhade, Q Thio, P Ogink, J Kim… - World neurosurgery, 2018 - Elsevier
Background Chordomas are locally invasive slow-growing tumors that are difficult to study
because of the rarity of the tumors and the lack of significant volumes of patients with …
because of the rarity of the tumors and the lack of significant volumes of patients with …
Chordomas: a review with emphasis on their pathophysiology, pathology, molecular biology, and genetics
G Karpathiou, JM Dumollard, M Dridi, P Dal Col… - … -Research and Practice, 2020 - Elsevier
Chordomas are uncommon, bone, axial, or (rarely) extra-axial tumors that are malignant and
frequently recur but less commonly metastasize. They usually affect adults, with a very small …
frequently recur but less commonly metastasize. They usually affect adults, with a very small …
[HTML][HTML] Prognostic molecular biomarkers in chordomas: a systematic review and identification of clinically usable biomarker panels
F Rubino, C Alvarez-Breckenridge, K Akdemir… - Frontiers in …, 2022 - frontiersin.org
Introduction and objective Despite the improvements in management and treatment of
chordomas over time, the risk of disease recurrence remains high. Consequently, there is a …
chordomas over time, the risk of disease recurrence remains high. Consequently, there is a …
[HTML][HTML] Clinicopathological and prognostic characteristics in dedifferentiated/poorly differentiated chordomas: a pooled analysis of individual patient data from 58 …
FS Liu, BW Zheng, TL Zhang, J Li, GH Lv… - Frontiers in …, 2021 - frontiersin.org
Background Currently, the clinicopathological and prognostic characteristics of
dedifferentiated chordoma (DC) and poorly differentiated chordoma (PDC) remain poorly …
dedifferentiated chordoma (DC) and poorly differentiated chordoma (PDC) remain poorly …
Radiotherapy after gross-total resection and subtotal resection of spinal chordoma: a SEER database analysis of overall survival outcomes
OBJECTIVE Chordomas are most frequently found in the sacrum, vertebral column, and
skull base. Achieving gross-total resection (GTR) has been shown to optimize overall …
skull base. Achieving gross-total resection (GTR) has been shown to optimize overall …