Immune signalling pathways convert pathogenic stimuli into cytosolic events that lead to the
resolution of infection. Upon ligand engagement, immune receptors together with their …

In this Primer, we focus on the most recent advancements in stimulated emission depletion
(STED) microscopy, encompassing optics, computational microscopy and probes design …

Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

Microporous annealed particle (MAP) scaffolds are injectable granular materials comprised
of micron sized hydrogel particles (microgels). The diameter of these microgels directly …

B lymphocytes recognize bacterial or viral antigens via different classes of the B cell antigen
receptor (BCR). Protrusive structures termed microvilli cover lymphocyte surfaces, and are …

Morphological transitions are typically attributed to the actions of proteins and lipids. Largely
overlooked in membrane shape regulation is the glycocalyx, a pericellular membrane coat …

Sensory neurons use specialized apical processes to perceive external stimuli and monitor
internal body conditions. The apical apparatus can include cilia, microvilli, or both, and is …

T cells sense and respond to their local environment at the nanoscale by forming small actin-
rich protrusions, called microvilli, which play critical roles in signaling and antigen …

T cells typically recognize their ligands using a defined cell biology—the scanning of their
membrane microvilli (MV) to palpate their environment—while that same membrane …

Motility is a crucial activity of immune cells allowing them to patrol tissues as they
differentiate, sample or exchange information, and execute their effector functions. Although …