Inflammatory bowel disease (IBD) is a general term for chronic or remitting/relapsing
inflammatory diseases of the intestinal tract and generally refers to ulcerative colitis (UC) …

Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Background The Selecting Therapeutic Targets in Inflammatory Bowel Disease (STRIDE)
initiative of the International Organization for the Study of Inflammatory Bowel Diseases …

Objective We aimed to provide an evidence-supported update of the ECCO-ESPGHAN
guideline on the medical management of paediatric Crohn's disease [CD]. Methods We …

Spondyloarthropathies (SpA) include many different forms of inflammatory arthritis and can
affect the spine (axial SpA) and/or peripheral joints (peripheral SpA) with Ankylosing …

Abstract Background and Aims This study aimed to compare real-world clinical effectiveness
and safety of vedolizumab, an α4β7-integrin inhibitor, and anti-tumour necrosis factor-α [anti …

Abstract Background and Aims We sought to analyze whether response to a second-line
biologic varies depending on the reason for discontinuation of the primary anti-TNF agent …

The goals for treatment of inflammatory bowel diseases (IBDs) are changing from
elimination of symptoms toward complete disease control—a process that demands both …

Background Both vedolizumab and ustekinumab can be considered for the treatment of
Crohn's disease (CD) when anti‐TNF treatment fails. However, head‐to‐head trials are …

Background Selective patient recruitment can produce discrepancies between clinical trial
results and real-world effectiveness. Methods A systematic literature review and meta …