Gene transcription regulation by ER at the single cell and allele level
F Stossi, AR Tostado, HL Johnson, RM Mistry… - Steroids, 2023 - Elsevier
In this short review we discuss the current view of how the estrogen receptor (ER), a pivotal
member of the nuclear receptor superfamily of transcription factors, regulates gene …
member of the nuclear receptor superfamily of transcription factors, regulates gene …
Characterization of flavonoids with potent and subtype-selective actions on estrogen receptors alpha and beta
The initial step in estrogen-regulated transcription is the binding of a ligand to its cognate
receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and …
receptors, named estrogen receptors (ERα and ERβ). Phytochemicals present in foods and …
[HTML][HTML] A novel ERβ high throughput microscopy platform for testing endocrine disrupting chemicals
DA Abbott, MG Mancini, MJ Bolt, AT Szafran… - Heliyon, 2024 - cell.com
In this study we present an inducible biosensor model for the Estrogen Receptor Beta (ERβ),
GFP-ERβ: PRL-HeLa, a single-cell-based high throughput (HT) in vitro assay that allows …
GFP-ERβ: PRL-HeLa, a single-cell-based high throughput (HT) in vitro assay that allows …
[HTML][HTML] Epigenetic Mechanisms of Endocrine-Disrupting Chemicals in Breast Cancer and Their Impact on Dietary Intake
DD Singh - Journal of Xenobiotics, 2024 - mdpi.com
Addressing the consequences of exposure to endocrine-disrupting chemicals (EDCs)
demands thorough research and elucidation of the mechanism by which EDCs negatively …
demands thorough research and elucidation of the mechanism by which EDCs negatively …
[HTML][HTML] Sensitive image-based chromatin binding assays using inducible ERα to rapidly characterize estrogenic chemicals and mixtures
Summary The United States Environmental Protection Agency (EPA) has been pursuing
new high throughput in vitro assays to characterize endocrine disrupting chemicals (EDCs) …
new high throughput in vitro assays to characterize endocrine disrupting chemicals (EDCs) …