The laser scanning confocal microscope (LSCM) is an essential tool for many biomedical
imaging applications at the level of the light microscope. The basic principles of confocal …

Microscopy of cells has changed dramatically since its early days in the mid-seventeenth
century. Image analysis has concurrently evolved from measurements of hand drawings and …

Determination of the structure of human plaque will be of great benefit in the prediction of its
formation and also the effects of treatment. However, a problem lies in the harvesting of …

The nuclear envelope consists of a doublemembraned extension of the rough endoplasmic
reticulum. In this report we describe long, dynamic tubular channels, derived from the …

The confocal laser scanning microscope (CLSM) has become a vital instrument for the
examination of subcellular structure, especially in fluorescently stained cells. Because of its …

High-resolution confocal microscopic images may be made of either the surface of a sample
or beneath the surface. These images can be likened to optical tomograms, giving thin (> …

Multiparameter fluorescence microscopy is often used to identify cell types and subcellular
organelles according to their differential labelling. For thick objects, the quantitative …

Confocal and two-photon fluorescence microscopy have advanced the exploration of
complex, three-dimensional biological structures at submicron resolution. We have …

This handbook focuses on physical paper testing in the laboratory and online. Divided into
five parts, it highlights assays for paper interactions with light, moisture, electricity, and heat …

Confocal microscopes have become a powerful tool of choice for researchers interested in
serious imaging of cell structure and function. These microscopes have revolutionized our …