Infection microenvironment-related antibacterial nanotherapeutic strategies
Z Wang, X Liu, Y Duan, Y Huang - Biomaterials, 2022 - Elsevier
The emergence and spread of antibiotic resistance is one of the biggest challenges in public
health. There is an urgent need to discover novel agents against the occurrence of multidrug …
health. There is an urgent need to discover novel agents against the occurrence of multidrug …
Tuftsin-bearing liposomes in treatment of macrophage-based infections
AK Agrawal, CM Gupta - Advanced drug delivery reviews, 2000 - Elsevier
The use of liposomes as drug carriers in treatment of various diseases has been explored
extensively for more than 20 years.'Conventional'liposomes, when administered in vivo by a …
extensively for more than 20 years.'Conventional'liposomes, when administered in vivo by a …
Tuftsin: on the 30-year anniversary of Victor Najjar's discovery
IZ Siemion, A Kluczyk - Peptides, 1999 - Elsevier
After a short description of the results of Victor Najjar's research on tuftsin and of the
discoveries done by other authors in the early stage of tuftsin investigation, the current state …
discoveries done by other authors in the early stage of tuftsin investigation, the current state …
Drug carriers in pharmaceutical design: promises and progress
RC Dutta - Current pharmaceutical design, 2007 - ingentaconnect.com
Ever since pure molecular entities have been adapted as drug, varied manifestations other
than elimination of infections are frequently been acknowledged as side effects …
than elimination of infections are frequently been acknowledged as side effects …
Tuftsin-bearing liposomes as rifampin vehicles in treatment of tuberculosis in mice
A Agarwal, H Kandpal, HP Gupta… - Antimicrobial agents …, 1994 - Am Soc Microbiol
The antitubercular activity of rifampin was considerably increased when it was encapsulated
in egg phosphatidylcholine liposomes. A further increase in the activity was observed when …
in egg phosphatidylcholine liposomes. A further increase in the activity was observed when …
Recent developments in drug delivery for treatment of tuberculosis by targeting macrophages
Tuberculosis (TB) is among the greatest public health and safety concerns in the 21st
century Mycobacterium tuberculosis, which causes TB, infects alveolar macrophages and …
century Mycobacterium tuberculosis, which causes TB, infects alveolar macrophages and …
Superior chemotherapeutic efficacy of amphotericin B in tuftsin-bearing liposomes against Leishmania donovani infection in hamsters
AK Agrawal, A Agrawal, A Pal, PY Guru… - Journal of drug …, 2002 - Taylor & Francis
Chemotherapeutic efficacy of the amphotericin B (Amp B), which is the drug of choice for
treatment of the leishmanial infections (kala-azar) that become resistant to the conventional …
treatment of the leishmanial infections (kala-azar) that become resistant to the conventional …
Tuftsin-bearing liposomes as antibiotic carriers in treatment of macrophage infections
CM Gupta, W Haq - Methods in enzymology, 2005 - Elsevier
Tuftsin is a tetrapeptide (Thr-Lys-Pro-Arg) that specifically binds monocytes, macrophages,
and polymorphonuclear leukocytes and potentiates their natural killer activity against tumors …
and polymorphonuclear leukocytes and potentiates their natural killer activity against tumors …
Tuftsin‐bearing liposomes as drug vehicles in the treatment of experimental aspergillosis
M Owais, I Ahmed, B Krishnakumar, RK Jaina… - FEBS …, 1993 - Wiley Online Library
Encapsulation of amphotericin B in tuftsin‐bearing liposomes greatly increased its efficacy in
treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased …
treatment of human aspergillosis in mice. Also, the drug efficacy was significantly increased …
[PDF][PDF] Liposomes in drug targeting
MK Basu - Biotechnology and Genetic Engineering Reviews, 1994 - Taylor & Francis
Liposomes are artificial vesicles composed of one or more concentric bi-layers which
enclose an aqueous space. Water-soluble drugs or biomolecules are known to be …
enclose an aqueous space. Water-soluble drugs or biomolecules are known to be …