Understanding and targeting anoikis in metastasis for cancer therapies

F Sattari Fard, N Jalilzadeh… - Cell biology …, 2023 - Wiley Online Library
The development of effective treatments for cancers requires investigations for a more
detailed and comprehensive understanding of the basic cellular mechanisms involved in …

[HTML][HTML] Matrix metalloproteinases in renal diseases: a critical appraisal

O Zakiyanov, M Kalousová, T Zima… - Kidney and Blood Pressure …, 2019 - karger.com
Matrix metalloproteinases (MMPs) are endopeptidases within the metzincin protein family
that not only cleave extracellular matrix (ECM) components, but also process the non-ECM …

Hyperthermia treatment as a promising anti-cancer strategy: therapeutic targets, perspective mechanisms and synergistic combinations in experimental approaches

GY Yi, MJ Kim, HI Kim, J Park, SH Baek - Antioxidants, 2022 - mdpi.com
Despite recent developments in diagnosis and treatment options, cancer remains one of the
most critical threats to health. Several anti-cancer therapies have been identified, but further …

pH/NIR light-controlled multidrug release via a mussel-inspired nanocomposite hydrogel for chemo-photothermal cancer therapy

A GhavamiNejad, M SamariKhalaj, LE Aguilar… - Scientific reports, 2016 - nature.com
This study reports on an intelligent composite hydrogel with both pH-dependent drug
release in a cancer environment and heat generation based on NIR laser exposure, for the …

Mechanisms of heat shock response in mammals

AK Velichko, EN Markova, NV Petrova… - Cellular and molecular …, 2013 - Springer
Heat shock (HS) is one of the best-studied exogenous cellular stresses. The cellular
response to HS utilizes ancient molecular networks that are based primarily on the action of …

Mechanism of cell death induced by magnetic hyperthermia with nanoparticles of γ-Mn x Fe 2–x O 3 synthesized by a single step process

NK Prasad, K Rathinasamy, D Panda… - Journal of Materials …, 2007 - pubs.rsc.org
Magnetic nanoparticles of γ-MnxFe2–xO3 (0≤ x≤ 1.3) have been synthesized successfully
using a single step process wherein the respective inorganic salts were thermally …

Matrix metalloproteinase inhibitors as anticancer therapeutics

F Mannello, G Tonti, S Papa - Current cancer drug targets, 2005 - ingentaconnect.com
Matrix metalloproteinases (MMPs), also designated as matrixins, play a central role in many
biological processes and are involved both in physiologic cellular processes and in …

Curcumin and 5-fluorouracil-loaded, folate-and transferrin-decorated polymeric magnetic nanoformulation: a synergistic cancer therapeutic approach, accelerated by …

S Balasubramanian, AR Girija, Y Nagaoka… - International journal …, 2014 - Taylor & Francis
The efficient targeting and therapeutic efficacy of a combination of drugs (curcumin and 5-
Fluorouracil [5FU]) and magnetic nanoparticles encapsulated poly (D, L-lactic-co-glycolic …

Multiple roles of matrix metalloproteinases during apoptosis

F Mannello, F Luchetti, E Falcieri, S Papa - Apoptosis, 2005 - Springer
Structural, molecular and biochemical approaches have contributed to piecing together the
puzzle of how matrix metalloproteinases (MMPs) work and contribute to various disease …

Treating cancer with heat: hyperthermia as promising strategy to enhance apoptosis

K Ahmed, SF Zaidi - Journal of Pakistan Medical Association, 2013 - ecommons.aku.edu
The fundamental idea and the effects of heat on cancer cells are well known. However, the
results obtained in therapy by hyperthermia (HT) alone have been only partially satisfactory …