Pathological changes of brain oscillations following ischemic stroke

Y Sato, O Schmitt, Z Ip, G Rabiller… - Journal of Cerebral …, 2022 - journals.sagepub.com
Brain oscillations recorded in the extracellular space are among the most important aspects
of neurophysiology data reflecting the activity and function of neurons in a population or a …

Advances in Optogenetics applications for central nervous system injuries

Y Geng, Z Li, J Zhu, C Du, F Yuan, X Cai, A Ali… - Journal of …, 2023 - liebertpub.com
Injuries to the central nervous system (CNS) often lead to severe neurological dysfunction
and even death. However, there are still no effective measures to improve functional …

[HTML][HTML] In vivo laser speckle contrast imaging of 4-aminopyridine-or pentylenetetrazole-induced seizures

Y Wang, V Tsytsarev, LD Liao - APL bioengineering, 2023 - pubs.aip.org
Clinical and preclinical studies on epileptic seizures are closely linked to the study of
neurovascular coupling. Obtaining reliable information about cerebral blood flow (CBF) in …

[HTML][HTML] Revisiting the effects of exercise on cerebral neurovascular functions in rats using multimodal assessment techniques

S Yen, HY Wu, Y Wang, CM Huang, CW Wu, JH Chen… - Iscience, 2023 - cell.com
Physical activity in the form of aerobic exercise has many beneficial effects on brain function.
Here, we aim to revisit the effects of exercise on brain morphology and neurovascular …

Sensory stimulation-based protection from impending stroke following MCA occlusion is correlated with desynchronization of widespread spontaneous local field …

W Rasheed, A Wodeyar, R Srinivasan, RD Frostig - Scientific reports, 2022 - nature.com
In a rat model of ischemic stroke by permanent occlusion of the medial cerebral artery
(pMCAo), we have demonstrated using continuous recordings by microelectrode array at the …

[HTML][HTML] Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI

S Yen, Y Wang, LD Liao - APL bioengineering, 2024 - pubs.aip.org
Type 1 diabetes mellitus (T1DM) can result in complications such as retinopathy,
nephropathy, and peripheral neuropathy, which can lead to brain dysfunction. In this study …

Topiramate suppresses peri-infarct spreading depolarization and improves outcomes in a rat model of photothrombotic stroke

Y Wang, S Yen, YYI Shih, CW Lai, YL Chen, LT Chen… - iScience, 2024 - cell.com
Ischemic stroke can cause depolarized brain waves, termed peri-infarct depolarization (PID).
Here, we evaluated whether topiramate, a neuroprotective drug used to treat epilepsy and …

Optogenetic excitation of ipsilesional sensorimotor neurons is protective in acute ischemic stroke: a laser speckle imaging study

B Bo, Y Li, W Li, Y Wang, S Tong - IEEE Transactions on …, 2018 - ieeexplore.ieee.org
Objective: Directly modulating targeted cortical function, brain stimulation provides
promising techniques for stroke intervention. However, the cellular level mechanisms …

Investigating Cerebral Neurovascular Responses to Hyperglycemia in a Rat Model of Type 2 Diabetes Using Multimodal Assessment Techniques

S Yen, Y Wang, LD Liao - iScience, 2024 - cell.com
To study neurovascular function in type 2 diabetes mellitus (T2DM), we established a high-
fat diet/streptozotocin (HFD/STZ) rat mode. Electrocorticography–laser speckle contrast …

Spatiotemporal dynamics of pial collateral blood flow following permanent middle cerebral artery occlusion in a rat model of sensory-based protection: a Doppler …

J Zhu, AM Hancock, L Qi, K Telkmann… - …, 2019 - spiedigitallibrary.org
There is a growing recognition regarding the importance of pial collateral flow in the
protection from impending ischemic stroke both in preclinical and clinical studies. Collateral …