Pathological changes of brain oscillations following ischemic stroke
Brain oscillations recorded in the extracellular space are among the most important aspects
of neurophysiology data reflecting the activity and function of neurons in a population or a …
of neurophysiology data reflecting the activity and function of neurons in a population or a …
Advances in Optogenetics applications for central nervous system injuries
Injuries to the central nervous system (CNS) often lead to severe neurological dysfunction
and even death. However, there are still no effective measures to improve functional …
and even death. However, there are still no effective measures to improve functional …
[HTML][HTML] In vivo laser speckle contrast imaging of 4-aminopyridine-or pentylenetetrazole-induced seizures
Y Wang, V Tsytsarev, LD Liao - APL bioengineering, 2023 - pubs.aip.org
Clinical and preclinical studies on epileptic seizures are closely linked to the study of
neurovascular coupling. Obtaining reliable information about cerebral blood flow (CBF) in …
neurovascular coupling. Obtaining reliable information about cerebral blood flow (CBF) in …
[HTML][HTML] Revisiting the effects of exercise on cerebral neurovascular functions in rats using multimodal assessment techniques
S Yen, HY Wu, Y Wang, CM Huang, CW Wu, JH Chen… - Iscience, 2023 - cell.com
Physical activity in the form of aerobic exercise has many beneficial effects on brain function.
Here, we aim to revisit the effects of exercise on brain morphology and neurovascular …
Here, we aim to revisit the effects of exercise on brain morphology and neurovascular …
Sensory stimulation-based protection from impending stroke following MCA occlusion is correlated with desynchronization of widespread spontaneous local field …
In a rat model of ischemic stroke by permanent occlusion of the medial cerebral artery
(pMCAo), we have demonstrated using continuous recordings by microelectrode array at the …
(pMCAo), we have demonstrated using continuous recordings by microelectrode array at the …
[HTML][HTML] Exploring the translational impact of type 1 diabetes on cerebral neurovascular function through ECoG-LSCI
S Yen, Y Wang, LD Liao - APL bioengineering, 2024 - pubs.aip.org
Type 1 diabetes mellitus (T1DM) can result in complications such as retinopathy,
nephropathy, and peripheral neuropathy, which can lead to brain dysfunction. In this study …
nephropathy, and peripheral neuropathy, which can lead to brain dysfunction. In this study …
Topiramate suppresses peri-infarct spreading depolarization and improves outcomes in a rat model of photothrombotic stroke
Y Wang, S Yen, YYI Shih, CW Lai, YL Chen, LT Chen… - iScience, 2024 - cell.com
Ischemic stroke can cause depolarized brain waves, termed peri-infarct depolarization (PID).
Here, we evaluated whether topiramate, a neuroprotective drug used to treat epilepsy and …
Here, we evaluated whether topiramate, a neuroprotective drug used to treat epilepsy and …
Optogenetic excitation of ipsilesional sensorimotor neurons is protective in acute ischemic stroke: a laser speckle imaging study
Objective: Directly modulating targeted cortical function, brain stimulation provides
promising techniques for stroke intervention. However, the cellular level mechanisms …
promising techniques for stroke intervention. However, the cellular level mechanisms …
Investigating Cerebral Neurovascular Responses to Hyperglycemia in a Rat Model of Type 2 Diabetes Using Multimodal Assessment Techniques
S Yen, Y Wang, LD Liao - iScience, 2024 - cell.com
To study neurovascular function in type 2 diabetes mellitus (T2DM), we established a high-
fat diet/streptozotocin (HFD/STZ) rat mode. Electrocorticography–laser speckle contrast …
fat diet/streptozotocin (HFD/STZ) rat mode. Electrocorticography–laser speckle contrast …
Spatiotemporal dynamics of pial collateral blood flow following permanent middle cerebral artery occlusion in a rat model of sensory-based protection: a Doppler …
There is a growing recognition regarding the importance of pial collateral flow in the
protection from impending ischemic stroke both in preclinical and clinical studies. Collateral …
protection from impending ischemic stroke both in preclinical and clinical studies. Collateral …