PcdA promotes orthogonal division plane selection in Staphylococcus aureus

F Ramos-León, BR Anjuwon-Foster… - Nature …, 2024 - nature.com
The bacterial pathogen, Staphylococcus aureus, grows by dividing in two alternating
orthogonal planes. How these cell division planes are positioned correctly is not known …

CoCoNuTs are a diverse subclass of Type IV restriction systems predicted to target RNA

RT Bell, H Sahakyan, KS Makarova, YI Wolf, EV Koonin - Elife, 2024 - elifesciences.org
A comprehensive census of McrBC systems, among the most common forms of prokaryotic
Type IV restriction systems, followed by phylogenetic analysis, reveals their enormous …

Multistep loading of a DNA sliding clamp onto DNA by replication factor C

M Schrecker, JC Castaneda, S Devbhandari, C Kumar… - Elife, 2022 - elifesciences.org
The DNA sliding clamp proliferating cell nuclear antigen (PCNA) is an essential co-factor for
many eukaryotic DNA metabolic enzymes. PCNA is loaded around DNA by the ATP …

The binding affinity‐dependent inhibition of cell growth and viability by DNA sulfur‐binding domains

Y Wang, F Ge, J Liu, W Hu, G Liu… - Molecular …, 2024 - Wiley Online Library
Increasing evidence suggests that DNA phosphorothioate (PT) modification serves several
purposes in the bacterial host, and some restriction enzymes specifically target PT‐DNA. PT …

Deep Spatio-Temporal Network for Low SNR Cryo-EM Movie Frame Enhancement

X Chong, H Leung, Q Li, J Yao… - IEEE/ACM Transactions …, 2024 - ieeexplore.ieee.org
Cryo-EM in single particle analysis is known to have low SNR and requires to utilize several
frames of the same particle sample to restore one high-quality image for visualizing that …

Insights into the structure-function relationship of the NorQ/NorD chaperones from Paracoccus denitrificans reveal shared principles of interacting MoxR AAA+/VWA …

M Kahle, S Appelgren, A Elofsson, M Carroni… - BMC biology, 2023 - Springer
Background NorQ, a member of the MoxR-class of AAA+ ATPases, and NorD, a protein
containing a Von Willebrand Factor Type A (VWA) domain, are essential for non-heme iron …

[HTML][HTML] Protein coopted from a phage restriction system dictates orthogonal cell division plane selection in Staphylococcus aureus

F Ramos-León, BR Anjuwon-Foster, V Anantharaman… - bioRxiv, 2023 - ncbi.nlm.nih.gov
The spherical bacterium Staphylococcus aureus, a leading cause of nosocomial infections,
undergoes binary fission by dividing in two alternating orthogonal planes, but the …

Structural analyses of the AAA+ ATPase domain of the transcriptional regulator GtrR in the BDSF quorum‐sensing system in Burkholderia cenocepacia

XF Yan, C Yang, M Wang, Y Yong, Y Deng… - FEBS …, 2022 - Wiley Online Library
Global transcriptional regulator downstream RpfR (GtrR) is a key downstream regulator for
quorum‐sensing signaling molecule cis‐2‐dodecenoic acid (BDSF). As a bacterial …

Astonishing diversity and multifaceted biological connections of Type IV restriction-modification systems.

RT Bell, J Juozapaitis, I Songailiene… - Biorxiv: the Preprint …, 2023 - europepmc.org
A comprehensive census of McrBC systems, a major form of prokaryotic Type IV
restrictionmodification (RM), followed by phylogenetic analysis, reveals their enormous …