Systemic pharmacological treatments for chronic plaque psoriasis: a network meta‐analysis
E Sbidian, A Chaimani, R Guelimi… - Cochrane Database …, 2023 - cochranelibrary.com
Background Psoriasis is an immune‐mediated disease with either skin or joints
manifestations, or both, and it has a major impact on quality of life. Although there is …
manifestations, or both, and it has a major impact on quality of life. Although there is …
Use of IL-23 inhibitors for the treatment of plaque psoriasis and psoriatic arthritis: a comprehensive review
Psoriasis is a common inflammatory skin disease with multiple comorbidities, including
psoriatic arthritis and coronary artery disease, that can severely impact an individual's …
psoriatic arthritis and coronary artery disease, that can severely impact an individual's …
Bimekizumab efficacy and safety in moderate to severe plaque psoriasis (BE READY): a multicentre, double-blind, placebo-controlled, randomised withdrawal phase …
KB Gordon, P Foley, JG Krueger, A Pinter, K Reich… - The Lancet, 2021 - thelancet.com
Background Bimekizumab is a monoclonal IgG1 antibody that selectively inhibits interleukin
(IL)-17F in addition to IL-17A. This study investigated the efficacy and safety of bimekizumab …
(IL)-17F in addition to IL-17A. This study investigated the efficacy and safety of bimekizumab …
Efficacy and safety of biologics for psoriasis and psoriatic arthritis and their impact on comorbidities: a literature review
M Kamata, Y Tada - International journal of molecular sciences, 2020 - mdpi.com
Psoriasis is a chronic inflammatory skin disease characterized by scaly indurated erythema.
It impairs patients' quality of life enormously. It has been recognized not only as a skin …
It impairs patients' quality of life enormously. It has been recognized not only as a skin …
A head‐to‐head comparison of ixekizumab vs. guselkumab in patients with moderate‐to‐severe plaque psoriasis: 24‐week efficacy and safety results from a …
A Blauvelt, C Leonardi, B Elewski… - British Journal of …, 2021 - academic.oup.com
Background Significantly more patients with moderate‐to‐severe plaque psoriasis treated
with the interleukin (IL)‐17A inhibitor ixekizumab vs. the IL‐23p19 inhibitor guselkumab in …
with the interleukin (IL)‐17A inhibitor ixekizumab vs. the IL‐23p19 inhibitor guselkumab in …
Ixekizumab and brodalumab indirect comparison in the treatment of moderate to severe psoriasis: Results from an Italian single‐center retrospective study in a real …
M Megna, L Potestio, E Camela… - Dermatologic …, 2022 - Wiley Online Library
Eleven biologic drugs are currently approved for psoriasis management. Real‐life studies
are needed to guide clinicians in choosing a tailored‐tail therapy. The aim of our …
are needed to guide clinicians in choosing a tailored‐tail therapy. The aim of our …
The TNF/IL‐23/IL‐17 axis—Head‐to‐head trials comparing different biologics in psoriasis treatment
LL Ten Bergen, A Petrovic… - Scandinavian …, 2020 - Wiley Online Library
Psoriasis is a T cell–mediated disease with autoimmune characteristics modulated by
genetic susceptibility along with environmental triggers. Inflammatory pathways marked with …
genetic susceptibility along with environmental triggers. Inflammatory pathways marked with …
The role of IL-17 cytokines in psoriasis
M Mosca, J Hong, E Hadeler, M Hakimi… - ImmunoTargets and …, 2021 - Taylor & Francis
Psoriasis is a chronic inflammatory skin condition associated with immune dysregulation.
The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically …
The immunologic cascade mediated by the interleukin (IL)-17 pathway plays a critically …
Psoriasis: Recent progress in molecular‐targeted therapies
M Honma, K Hayashi - The Journal of Dermatology, 2021 - Wiley Online Library
Psoriasis is a multifactorial recalcitrant inflammatory skin disease characterized by
bothersome scaly reddish plaques especially on frequently chafed body parts, such as the …
bothersome scaly reddish plaques especially on frequently chafed body parts, such as the …
Efficacy, safety, and drug survival of IL-23, IL-17, and TNF-alpha inhibitors for psoriasis treatment: a retrospective study
P Dapavo, N Siliquini, L Mastorino… - Journal of …, 2022 - Taylor & Francis
Background Real-life studies in psoriasis are lacking. Many monoclonal antibodies targeting
tumor-necrosis factor (TNF)-alpha, interleukin 17, and 23 are approved drugs for psoriasis …
tumor-necrosis factor (TNF)-alpha, interleukin 17, and 23 are approved drugs for psoriasis …