13C MRS studies of neuroenergetics and neurotransmitter cycling in humans
In the last 25 years, 13 C MRS has been established as the only noninvasive method for the
measurement of glutamate neurotransmission and cell‐specific neuroenergetics. Although …
measurement of glutamate neurotransmission and cell‐specific neuroenergetics. Although …
In vivo 13C and 1H‐[13C] MRS studies of neuroenergetics and neurotransmitter cycling, applications to neurological and psychiatric disease and brain cancer
In the last 25 years 13C MRS has been established as the only noninvasive method for
measuring glutamate neurotransmission and cell specific neuroenergetics. Although …
measuring glutamate neurotransmission and cell specific neuroenergetics. Although …
In vivo 13C NMR spectroscopy and metabolic modeling in the brain: a practical perspective
In vivo 13C NMR spectroscopy has the unique capability to measure metabolic fluxes
noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis …
noninvasively in the brain. Quantitative measurements of metabolic fluxes require analysis …
Quantitative fMRI and oxidative neuroenergetics
F Hyder, DL Rothman - Neuroimage, 2012 - Elsevier
The discovery of functional magnetic resonance imaging (fMRI) has greatly impacted
neuroscience. The blood oxygenation level-dependent (BOLD) signal, using …
neuroscience. The blood oxygenation level-dependent (BOLD) signal, using …
Characterization of the metabolic phenotype of chronically activated lymphocytes
DR Wahl, B Petersen, R Warner, BC Richardson… - Lupus, 2010 - journals.sagepub.com
Activated lymphocytes proliferate, secrete cytokines, and can make antibodies. Normally
activated B and T cells meet the bioenergetic demand for these processes by up-regulating …
activated B and T cells meet the bioenergetic demand for these processes by up-regulating …
Advances in imaging brain metabolism
F Hyder, DL Rothman - Annual review of biomedical …, 2017 - annualreviews.org
Metabolism is central to neuroimaging because it can reveal pathways by which neuronal
and glial cells use nutrients to fuel their growth and function. We focus on advanced …
and glial cells use nutrients to fuel their growth and function. We focus on advanced …
A computational model of neuro-glio-vascular loop interactions
BS Chander, VS Chakravarthy - PloS one, 2012 - journals.plos.org
We present a computational, biophysical model of neuron-astrocyte-vessel interaction.
Unlike other cells, neurons convey “hunger” signals to the vascular network via an …
Unlike other cells, neurons convey “hunger” signals to the vascular network via an …
A flux balance of glucose metabolism clarifies the requirements of the Warburg effect
The Warburg effect, or aerobic glycolysis, is marked by the increased metabolism of glucose
to lactate in the presence of oxygen. Despite its widespread prevalence in physiology and …
to lactate in the presence of oxygen. Despite its widespread prevalence in physiology and …
Regulation of blood flow in activated human brain by cytosolic NADH/NAD+ ratio
AG Vlassenko, MM Rundle… - Proceedings of the …, 2006 - National Acad Sciences
It has been known for more than a century that increases in neuronal activity in the brain are
reliably accompanied by changes in local blood flow. More recently it has been appreciated …
reliably accompanied by changes in local blood flow. More recently it has been appreciated …
pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study
Early diagnosis and follow-up of neurodegenerative diseases are often hampered by the
lack of reliable biomarkers. Neuroimaging techniques like magnetic resonance …
lack of reliable biomarkers. Neuroimaging techniques like magnetic resonance …