Resistance to immune checkpoint therapies by tumour-induced T-cell desertification and exclusion: key mechanisms, prognostication and new therapeutic …
Immune checkpoint therapies (ICT) can reinvigorate the effector functions of anti-tumour T
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …
cells, improving cancer patient outcomes. Anti-tumour T cells are initially formed during their …
[HTML][HTML] Vitreoretinal lymphoma
B Sobolewska, SP Chee, F Zaguia, DA Goldstein… - Cancers, 2021 - mdpi.com
Simple Summary Vitreoretinal lymphoma is a variant of primary CNS lymphoma involving
the retina and/or the vitreous. At the time of presentation, CNS involvement occurs in up to …
the retina and/or the vitreous. At the time of presentation, CNS involvement occurs in up to …
The molecular hallmarks of primary and secondary vitreoretinal lymphoma
I Bonzheim, P Sander, J Salmerón-Villalobos… - Blood …, 2022 - ashpublications.org
Vitreoretinal lymphoma (VRL) is a rare subtype of diffuse large B-cell lymphoma (DLBCL)
considered a variant of primary central nervous system lymphoma (PCNSL). The diagnosis …
considered a variant of primary central nervous system lymphoma (PCNSL). The diagnosis …
Oncogenic mutations of MYD88 and CD79B in diffuse large B-cell lymphoma and implications for clinical practice
Simple Summary A diagnosis of diffuse large B-cell lymphoma in our therapeutic era should
be implemented by the definition of the cell of origin, additional immunohistochemistry (ie …
be implemented by the definition of the cell of origin, additional immunohistochemistry (ie …
Primary vitreoretinal lymphoma: Current diagnostic laboratory tests and new emerging molecular tools
B Melli, P Gentile, D Nicoli, E Farnetti, S Croci, F Gozzi… - Current …, 2022 - mdpi.com
Primary vitreoretinal lymphoma (PVRL), a rare aggressive malignancy primarily involving
the retina and/or the vitreous, is a major diagnostic challenge for clinicians (who commonly …
the retina and/or the vitreous, is a major diagnostic challenge for clinicians (who commonly …
New insights into immunological therapy for retinal disorders
A Takeda, R Yanai, Y Murakami, M Arima… - Frontiers in …, 2020 - frontiersin.org
In the twentieth century, a conspicuous lack of effective treatment strategies existed for
managing several retinal disorders, including age-related macular degeneration; diabetic …
managing several retinal disorders, including age-related macular degeneration; diabetic …
High-throughput microRNA profiling of vitreoretinal lymphoma: vitreous and serum microRNA profiles distinct from uveitis
T Minezaki, Y Usui, M Asakage, M Takanashi… - Journal of Clinical …, 2020 - mdpi.com
Purpose: Vitreoretinal lymphoma (VRL) is a non-Hodgkin lymphoma of the diffuse large B
cell type (DLBCL), which is an aggressive cancer causing central nervous system related …
cell type (DLBCL), which is an aggressive cancer causing central nervous system related …
Primary CNS lymphoma: update on molecular pathogenesis and therapy
SS Mo, J Cleveland, JL Rubenstein - Leukemia & Lymphoma, 2023 - Taylor & Francis
Primary central nervous system lymphoma (PCNSL) is a rare and aggressive form of extra-
nodal non-Hodgkin lymphoma that as a brain tumor poses a unique set of challenges in …
nodal non-Hodgkin lymphoma that as a brain tumor poses a unique set of challenges in …
Cytologic and molecular diagnostics for vitreoretinal lymphoma: current approaches and emerging single-cell analyses
WJ Tan, MM Wang, P Ricciardi-Castagnoli… - Frontiers in Molecular …, 2021 - frontiersin.org
Vitreoretinal lymphoma (VRL) is a rare ocular malignancy that manifests as diffuse large B-
cell lymphoma. Early and accurate diagnosis is essential to prevent mistreatment and to …
cell lymphoma. Early and accurate diagnosis is essential to prevent mistreatment and to …
Applying single-cell technology in uveal melanomas: current trends and perspectives for improving uveal melanoma metastasis surveillance and tumor profiling
Uveal melanoma (UM) is the most common primary adult intraocular malignancy. This rare
but devastating cancer causes vision loss and confers a poor survival rate due to distant …
but devastating cancer causes vision loss and confers a poor survival rate due to distant …