Advances in the genetic characterization of the malaria vector, Anopheles funestus, and implications for improved surveillance and control

JO Odero, IH Nambunga, DW Wangrawa, A Badolo… - Malaria Journal, 2023 - Springer
Anopheles mosquitoes present a major public health challenge in sub-Saharan Africa;
notably, as vectors of malaria that kill over half a million people annually. In parts of the east …

Anopheles rufipes implicated in malaria transmission both indoors and outdoors alongside Anopheles funestus and Anopheles arabiensis in rural south-east …

K Saili, C De Jager, OP Sangoro, TE Nkya… - Malaria Journal, 2023 - Springer
Background The primary malaria vector-control interventions, indoor residual spraying and
long-lasting insecticidal nets, are effective against indoor biting and resting mosquito …

Genomics reveals heterogeneous Plasmodium falciparum transmission and selection signals in Zambia

AA Fola, Q He, S Xie, J Thimmapuram… - Communications …, 2024 - nature.com
Background Genomic surveillance is crucial for monitoring malaria transmission and
understanding parasite adaptation to interventions. Zambia lacks prior nationwide efforts in …

Association between indoor residual spraying and the malaria burden in Zambia and factors associated with IRS refusals: a case-control study in Vubwi District

WX Zhang, Y Zhou, E Tembo, J Du, SS Zhang… - Parasites & …, 2024 - Springer
Background Indoor residual spraying (IRS) has been implemented to prevent malaria in
Zambia for several decades, but its effectiveness has not been evaluated long term and in …

Community perceptions, acceptability, and the durability of house screening interventions against exposure to malaria vectors in Nyimba district, Zambia

K Saili, C de Jager, F Masaninga, B Chisanga… - BMC Public Health, 2024 - Springer
Background House screening remains conspicuously absent in national malaria programs
despite its recognition by the World Health Organization as a supplementary malaria vector …

Malaria situation and elimination in Africa with specific focus on Zimbabwe: a systematic review

Z Makuvara, SR Magano, G Mugumbate - Cogent Public Health, 2024 - Taylor & Francis
Malaria is an infectious disease caused protozoa in genus Plasmodium. In spite of the efforts
made in the fight against malaria, this tropic infectious disease is still one of the most …

[HTML][HTML] Diversity and selection analyses identify transmission-blocking antigens as the optimal vaccine candidates in Plasmodium falciparum

II Ciubotariu, BK Broyles, S Xie, J Thimmapuram… - medRxiv, 2024 - ncbi.nlm.nih.gov
Background A highly effective vaccine for malaria remains an elusive target, at least in part
due to the under-appreciated natural parasite variation. This study aimed to investigate …

[HTML][HTML] Genomics reveals heterogeneous Plasmodium falciparum transmission and population differentiation in Zambia and bordering countries

AA Fola, Q He, S Xie, J Thimmapuram, KP Bhide… - medRxiv, 2024 - ncbi.nlm.nih.gov
Genomic surveillance plays a critical role in monitoring malaria transmission and
understanding how the parasite adapts in response to interventions. We conducted genomic …

[HTML][HTML] Molecular Detection and Phylogenetic Characterization of Rickettsia in Ticks Collected from Leopard Tortoise (Geochelone pardalis) in rural Zambia

CS Khumalo, M Mulavu, K Changula, B Mubemba… - Science in One …, 2024 - Elsevier
Abstract In sub-Saharan Africa, limited studies have investigated zoonotic pathogens that
may be harboured by ticks infesting reptiles such as tortoises. Here, we report the presence …

Supplementing routine hospital surveillance of malaria to capture excess mortality and epidemiological trends: a five-year observational study

JBB Kabuya, C Bond, M Hauser, J Sikalima… - Frontiers in …, 2024 - frontiersin.org
Introduction Malaria surveillance in Africa is conducted largely through health facility-based
health management information systems (HMIS) which provide aggregated data to malaria …